24095-80-5

• 常用中文名：1-[3,5-bis(trifluoromethyl)anilino]-3-methylthiourea
• 常用英文名：1-[3,5-bis(trifluoromethyl)anilino]-3-methylthiourea
• CAS号：24095-80-5
• 分子式：C₁₀H₉F₆N₃S
• 分子量：317.25400
• 发布时间：2017-11-08 08:08:13
• 更新时间：2025-09-26 18:16:59

名称

• 英文名: 1-[3,5-bis(trifluoromethyl)anilino]-3-methylthiourea
• 英文别名: Ciba 2696-Go; C 2696-Go; Go 2696

物化性质

• 密度: 1.475g/cm3
• 沸点: 258.5ºC at 760 mmHg
• 分子式: C₁₀H₉F₆N₃S
• 分子量: 317.25400
• 闪点: 110.1ºC
• 精确质量: 317.04200
• PSA: 75.22000
• LogP: 4.02020
• 蒸汽压: 0.0137mmHg at 25°C
• 折射率: 1.515
• 储存条件: 库房通风低温干燥,与氧化剂、酸类分开存放

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VT3350000 CHEMICAL NAME : Semicarbazide, 1-(alpha,alpha,alpha,alpha',alpha',alpha'-hexafluoro- 3,5-xylyl)-4-methyl- 3-thio- CAS REGISTRY NUMBER : 24095-80-5 LAST UPDATED : 199612 DATA ITEMS CITED : 9 MOLECULAR FORMULA : C10-H9-F6-N3-S MOLECULAR WEIGHT : 317.28 WISWESSER LINE NOTATION : SUYM1&MMR CXFFF EXFFF HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 414 mg/kg TOXIC EFFECTS : Behavioral - ataxia Behavioral - coma Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,797,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 212 mg/kg TOXIC EFFECTS : Behavioral - ataxia Behavioral - coma Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,797,1973 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 269 mg/kg TOXIC EFFECTS : Behavioral - ataxia Behavioral - coma Nutritional and Gross Metabolic - weight loss or decreased weight gain REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,797,1973 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,797,1973 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Primate - monkey DOSE/DURATION : >1500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,797,1973 ** REPRODUCTIVE DATA ** TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 25 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - eye/ear REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,797,1973 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 50 mg/kg SEX/DURATION : female 6-15 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 23,797,1973 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 30 mg/kg SEX/DURATION : female 1-3 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 23,1243,1984 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 7500 ug/kg SEX/DURATION : female 1-3 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : IJSBDB Indian Journal of Chemistry, Section B: Organic Chemistry, Including Medicinal Chemistry. (Publications & Information Directorate, Council of Scientific and Industrial Research (CSIR), Hillside Rd., New Delhi 110 012, India) V.14B- 1976- Volume(issue)/page/year: 23,1243,1984

安全

• 海关编码: 2930909090

合成路线

90475-89-1 ~% 24095-80-5

文献：Nagarajan, K.; Talwalker, P.K.; Kulkarni, C.L.; Venkateswarlu, A.; Prabhu, S.S.; Nayak, G.V. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1243 - 1257

328-74-5 ~% 24095-80-5

文献：Nagarajan, K.; Talwalker, P.K.; Kulkarni, C.L.; Venkateswarlu, A.; Prabhu, S.S.; Nayak, G.V. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1243 - 1257

886-35-1 556-61-6 ~% 24095-80-5

文献：Nagarajan, K.; Talwalker, P.K.; Kulkarni, C.L.; Venkateswarlu, A.; Prabhu, S.S.; Nayak, G.V. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1984 , vol. 23, # 12 p. 1243 - 1257

海关

海关编码	2930909090
中文概述	2930909090. 其他有机硫化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%