18260-92-9

• 常用中文名：6-氯-2,5-二甲基嘧啶-4-胺
• 常用英文名：6-chloro-2,5-dimethylpyrimidin-4-amine
• CAS号：18260-92-9
• 分子式：C₆H₈ClN₃
• 分子量：157.60100
• 发布时间：2019-01-30 11:25:02
• 更新时间：2025-09-10 11:09:34

名称

• 中文名: 6-氯-2,5-二甲基-嘧啶-4-胺
• 英文名: 6-chloro-2,5-dimethylpyrimidin-4-amine
• 中文别名: 6-氯-2,5-二甲基嘧啶-4-胺
• 英文别名: 4-Amino-6-chlor-2,5-dimethyl-pyrimidin; 6-Chlor-4-amino-2,5-dimethylpyrimidin; 6-Chlor-2,5-dimethyl-pyrimidin-4-ylamin; 4-Amino-6-chloro-2,5-dimethylpyrimidine; 6-Chloro-2,5-dimethyl-pyrimidine-4-ylamine; 6-Chloro-2,5-dimethyl-4-pyrimidinamine; Pyrimidine,4-amino-6-chloro-2,5-dimethyl; 6-chloro-2,5-dimethyl-pyrimidin-4-ylamine

物化性质

• 密度: 1.284g/cm3
• 沸点: 279.7ºC at 760 mmHg
• 分子式: C₆H₈ClN₃
• 分子量: 157.60100
• 闪点: 123ºC
• 精确质量: 157.04100
• PSA: 52.53000
• LogP: 1.25910
• 蒸汽压: 0.00394mmHg at 25°C
• 折射率: 1.586
• 储存条件: 2-8°C，避光，保存于惰性气体中

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV6329550 CHEMICAL NAME : Pyrimidine, 4-amino-6-chloro-2,5-dimethyl- CAS REGISTRY NUMBER : 18260-92-9 BEILSTEIN REFERENCE NO. : 0126825 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C6-H8-Cl-N3 MOLECULAR WEIGHT : 157.62 WISWESSER LINE NOTATION : T6N CNJ B1 DZ E1 FG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 339 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 11,495,1963

安全

• 海关编码: 2933599090

合成路线

1780-33-2 ~% 18260-92-9

文献：SUNOVION PHARMACEUTICALS INC.; CAMPBELL, John, Emerson; HEWITT, Michael, Charles; JONES, Philip; XIE, Linghong Patent: WO2011/150156 A2, 2011 ; Location in patent: Page/Page column 124 ; WO 2011/150156 A2

857412-07-8 ~% 18260-92-9

文献：Henze et al. Journal of Organic Chemistry, 1952 , vol. 17, p. 1320,1322

1194-74-7 ~% 18260-92-9

文献：SUNOVION PHARMACEUTICALS INC.; CAMPBELL, John, Emerson; HEWITT, Michael, Charles; JONES, Philip; XIE, Linghong Patent: WO2011/150156 A2, 2011 ; WO 2011/150156 A2

上下游产品

上游产品  3
1780-33-2 857412-07-8 1194-74-7
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海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%