5379-97-5

• 常用中文名：diethyl 2-acetamido-2-(1H-indol-3-ylmethyl)propanedioate
• 常用英文名：diethyl 2-acetamido-2-(1H-indol-3-ylmethyl)propanedioate
• CAS号：5379-97-5
• 分子式：C₁₈H₂₂N₂O₅
• 分子量：346.37800
• 发布时间：2016-02-24 21:49:38
• 更新时间：2024-01-23 14:36:01

名称

• 英文名: diethyl 2-acetamido-2-(1H-indol-3-ylmethyl)propanedioate
• 英文别名: Acetylamino-indol-3-ylmethyl-malonsaeure-diaethylester; acetylamino-indol-3-ylmethyl-malonic acid diethyl ester

物化性质

• 密度: 1.238g/cm3
• 沸点: 551.3ºC at 760 mmHg
• 分子式: C₁₈H₂₂N₂O₅
• 分子量: 346.37800
• 闪点: 287.2ºC
• 精确质量: 346.15300
• PSA: 97.49000
• LogP: 2.10240
• 折射率: 1.573

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TY1700000 CHEMICAL NAME : Propanedioic acid, (acetylamino)(1H-indol-3-ylmethyl)-, diethyl ester CAS REGISTRY NUMBER : 5379-97-5 BEILSTEIN REFERENCE NO. : 0338581 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C18-H22-N2-O5 MOLECULAR WEIGHT : 346.42 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >692 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : YKKZAJ Yakugaku Zasshi. Journal of Pharmacy. (Nippon Yakugakkai, 2-12-15 Shibuya, Shibuya-ku, Tokyo 150, Japan) No.1- 1881- Volume(issue)/page/year: 94,1620,1974

合成路线

87-52-5 1068-90-2 ~99% 5379-97-5

文献：Somei, Masanori; Karasawa, Yoshio; Kaneko, Chikara Heterocycles, 1981 , vol. 16, # 6 p. 941 - 949

6297-96-7 ~% 5379-97-5

文献：Dow Chem. Co. Patent: US2701800 , 1951 ;

120-72-9 ~% 5379-97-5

文献：Snyder; Matteson Journal of the American Chemical Society, 1957 , vol. 79, p. 2217,2219

22687-14-5 1068-90-2 ~% 5379-97-5

文献：Snyder; Matteson Journal of the American Chemical Society, 1957 , vol. 79, p. 2217,2219

5457-31-8 30412-43-2 ~% 5379-97-5

文献：Snyder; Smith Journal of the American Chemical Society, 1944 , vol. 66, p. 350

1068-90-2 ~% 5379-97-5

文献：Chibata; Yamada Bulletin of the Agricultural Chemical Society of Japan, 1957 , vol. 21, p. 58

上下游产品

上游产品  7
87-52-5 1068-90-2 6297-96-7 120-72-9
22687-14-5 5457-31-8 30412-43-2
下游产品  5
10022-82-9 26988-72-7 54-12-6 6976-19-8
42717-06-6