72238-02-9

• 常用中文名：N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)propane-1,3-diamine
• 常用英文名：N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)propane-1,3-diamine
• CAS号：72238-02-9
• 分子式：C₂₅H₃₂N₄O
• 分子量：404.54800
• 发布时间：2018-06-22 06:43:18
• 更新时间：2024-01-19 06:40:11

名称

• 英文名: N',N'-diethyl-N-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)propane-1,3-diamine
• 英文别名: 1-((3-(Diethylamino)propyl)amino)-5,11-dimethyl-9-methoxy-6H-pyrido(4,3-b)carbazole; Reteliptina [Spanish]; Petelliptine [French]; BD-84; 1-<<3-(diethylamino)propyl>amino>-5,11-dimethyl-6H-pyrido<4,3-b>carbazole; Retelliptine; 6H-Pyrido(4,3-b)carbazole,1-((3-diethylamino)propylamino)-5,11-dimethyl-9-methoxy; N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazol-1-yl)-propane-1,3-diamine; Retelliptinum [Latin]; 1-((3-(Diethylamino)propyl)amino)-9-methoxy-5,11-dimethyl-6H-pyrido(4,3-b)carbazole

物化性质

• 密度: 1.17g/cm3
• 沸点: 626.8ºC at 760 mmHg
• 分子式: C₂₅H₃₂N₄O
• 分子量: 404.54800
• 闪点: 332.9ºC
• 精确质量: 404.25800
• PSA: 53.18000
• LogP: 5.71150
• 折射率: 1.674

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TX7387000 CHEMICAL NAME : 1,3-Propanediamine, N,N-diethyl-N'-(9-methoxy-5,11-dimethyl-6H-pyrido(4,3 -b)carbazol-1-yl)- CAS REGISTRY NUMBER : 72238-02-9 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C25-H32-N4-O MOLECULAR WEIGHT : 404.61 WISWESSER LINE NOTATION : T D6 B656 FN LMJ C1 EM3N2&2 J1 PO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 60 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,181,1983 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 60 mg/kg TOXIC EFFECTS : Tumorigenic - active as anti-cancer agent Biochemical - Metabolism (Intermediary) - effect on inflammation or mediation of inflammation REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,1212,1980

合成路线

72237-98-0 104-78-9 ~85% 72238-02-9

文献：Dormoy; Heymes Tetrahedron, 1993 , vol. 49, # 14 p. 2915 - 2938

148729-98-0 ~% 72238-02-9

文献：Dormoy; Heymes Tetrahedron, 1993 , vol. 49, # 14 p. 2915 - 2938

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