52010-22-7

• 常用中文名：4-氯-3H-1-异苯并呋喃酮
• 常用英文名：4-Chlorophthalide
• CAS号：52010-22-7
• 分子式：C₈H₅ClO₂
• 分子量：168.57700
• 发布时间：2018-09-01 11:36:59
• 更新时间：2024-01-12 19:56:33

名称

• 中文名: 4-氯-3H-1-异苯并呋喃酮
• 英文名: 4-Chlorophthalide
• 英文别名: 4-chloro-3H-2-benzofuran-1-one; 4-Chloroisobenzofuran-1(3H)-one

物化性质

• 密度: 1.428g/cm3
• 沸点: 360.6ºC at 760mmHg
• 分子式: C₈H₅ClO₂
• 分子量: 168.57700
• 闪点: 203.5ºC
• 精确质量: 167.99800
• PSA: 26.30000
• LogP: 2.01040
• 折射率: 1.601
• 储存条件: 室温，干燥

MSDS

Material Safety Data Sheet Section1. Identification of the substance Product Name: 4-Chlorophthalide Synonyms: Section2. Hazards identification Harmful by inhalation, in contact with skin, and if swallowed. Section3. Composition/information on ingredients. Ingredient name:4-Chlorophthalide CAS number:52010-22-7 Section4. First aid measures Skin contact:Immediately wash skin with copious amounts of water for at least 15 minutes while removing contaminated clothing and shoes. If irritation persists, seek medical attention. Eye contact:Immediately wash skin with copious amounts of water for at least 15 minutes. Assure adequate flushing of the eyes by separating the eyelids with fingers. If irritation persists, seek medical attention. Inhalation:Remove to fresh air. In severe cases or if symptoms persist, seek medical attention. Ingestion:Wash out mouth with copious amounts of water for at least 15 minutes. Seek medical attention. Section5. Fire fighting measures In the event of a fire involving this material, alone or in combination with other materials, use dry powder or carbon dioxide extinguishers. Protective clothing and self-contained breathing apparatus should be worn. Section6. Accidental release measures Personal precautions: Wear suitable personal protective equipment which performs satisfactorily and meets local/state/national standards. Respiratory precaution:Wear approved mask/respirator Hand precaution:Wear suitable gloves/gauntlets Skin protection:Wear suitable protective clothing Eye protection:Wear suitable eye protection Methods for cleaning up: Mix with sand or similar inert absorbent material, sweep up and keep in a tightly closed container for disposal. See section 12. Environmental precautions: Do not allow material to enter drains or water courses. Section7. Handling and storage Handling:This product should be handled only by, or under the close supervision of, those properly qualified in the handling and use of potentially hazardous chemicals, who should take into account the fire, health and chemical hazard data given on this sheet. Store in closed vessels. Storage: Section8. Exposure Controls / Personal protection Engineering Controls: Use only in a chemical fume hood. Personal protective equipment: Wear laboratory clothing, chemical-resistant gloves and safety goggles. General hydiene measures: Wash thoroughly after handling. Wash contaminated clothing before reuse. Section9. Physical and chemical properties Appearance:Not specified Boiling point:No data No data Melting point: Flash point:No data Density:No data Molecular formula:C8H5ClO2 Molecular weight:168.6 Section10. Stability and reactivity Conditions to avoid: Heat, flames and sparks. Materials to avoid: Oxidizing agents. Possible hazardous combustion products: Carbon monoxide, hydrogen chloride. Section11. Toxicological information No data. Section12. Ecological information No data. Section13. Disposal consideration Arrange disposal as special waste, by licensed disposal company, in consultation with local waste disposal authority, in accordance with national and regional regulations. Section14. Transportation information Non-harzardous for air and ground transportation. Section15. Regulatory information No chemicals in this material are subject to the reporting requirements of SARA Title III, Section 302, or have known CAS numbers that exceed the threshold reporting levels established by SARA Title III, Section 313. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NP7000000 CHEMICAL NAME : 1(3H)-Isobenzofuranone, 4-chloro- CAS REGISTRY NUMBER : 52010-22-7 BEILSTEIN REFERENCE NO. : 0124386 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H5-Cl-O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : NNGADV Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. (Nippon Noyaku Gakkai, 1-43-11, Komagome, Toshima-ku, Tokyo 170, Japan) V.1- 1976- Volume(issue)/page/year: 1,283,1976

安全

• 海关编码: 2932209090

合成路线

117-21-5 ~% 52010-22-7 70097-45-9

文献：Nikulin, V. I.; Pisarenko, L. M. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1985 , vol. 34, # 1 p. 141 - 144 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1985 , # 1 p. 151 - 155

59434-19-4 ~65% 52010-22-7

文献：Wang, Wei; Cha, Xue-Xiang; Reiner, John; Gao, Yuan; Qiao, Hai-Ling; Shen, Jia-Xiang; Chang, Jun-Biao European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1941 - 1946

117-21-5 ~0% 52010-22-7 70097-45-9 110706-48-4

文献：Soucy, C.; Favreau, D.; Kayser, M. M. Journal of Organic Chemistry, 1987 , vol. 52, # 1 p. 129 - 134

615-60-1 608-23-1 ~% 54109-03-4 52010-22-7 详细

文献：General Electric Company Patent: US6670487 B1, 2003 ; Location in patent: Page column 15 ;

608-23-1 ~% 52010-22-7

文献：Soucy, C.; Favreau, D.; Kayser, M. M. Journal of Organic Chemistry, 1987 , vol. 52, # 1 p. 129 - 134

27563-65-1 ~% 52010-22-7

文献：Soucy, C.; Favreau, D.; Kayser, M. M. Journal of Organic Chemistry, 1987 , vol. 52, # 1 p. 129 - 134

上下游产品

上游产品  5
117-21-5 59434-19-4 615-60-1 608-23-1
27563-65-1
下游产品  1
110706-48-4

海关

海关编码	2932209090
中文概述	2932209090. 其他内酯. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%