15690-38-7

• 常用中文名：羟甲基-7-氨基头孢烷酸
• 常用英文名：7-Amino-deacetylcephalosporanic Acid
• CAS号：15690-38-7
• 分子式：C₈H₁₀N₂O₄S
• 分子量：230.241
• 相关类别： 原料药 抗生素类药物 头孢菌素类药
• 发布时间：2018-09-12 19:00:36
• 更新时间：2026-07-15 11:55:02
• Deacetyl-7-aminocephalosporanic acid is intermediate in the semi-synthetic cephalosporins synthesis. It is found in Acremonium chrysogenum.

名称

• 中文名: 羟甲基-7-氨基头孢烷酸
• 英文名: 7-Amino-deacetylcephalosporanic Acid
• 中文别名: (6R,7R)-7-氨基-3-(羟甲基)-8-氧代-5-噻-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸; 头孢呋辛杂质23; 头孢噻肟钠杂质13; 7-ACA 杂质1(去乙酰7-ACA ); (6R,7R)-7-氨基-3-(羟甲基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-羧酸; 7-ACA 有关杂质 1(去乙酰 7-ACA); 去乙酰基-7-氨基头孢菌烷酸; 7Β-氨基-3-羟甲基-3-头孢烯-4-羧酸; 脱乙酰-7-氨基头孢烷酸; 脱乙酰-7-AMINOCHALOSPORANIC ACID; 头孢西酮杂质 11; 7-氨基-3-(羟基甲基)-3-头孢环-4-羧酸; 头孢菌素杂质A; 羟甲基-7-氨基头孢烷酸(-ACA); 头孢曲松杂质 22; 去乙酰 - 7 - 氨基头孢烷酸(D-7-ACA); 7-氨基 - 脱乙酰头孢烷酸; 7-氨基头孢烷酸杂质4; 7-ACA杂质D; 7-ACA 有关杂质; 头孢西酮有关杂质 11; 去乙酰7-ACA(D-7-ACA); 头孢西酮有关杂质 10; 去乙酰7-ACA; (6R,7R)-7-氨基-3-(羟甲基)-8-氧代-5-硫杂-1-氮杂双环[4.2.0]辛-2-烯-2-甲酸; 7-氨基-3-去乙酰基-头孢烷酸,D-7ACA; 头孢菌素杂质7; 头孢呋辛杂质36; 7-氨基脱乙酰基头孢烷酸; 乙酰-7-氨基头孢烷酸; 脱乙酰-7-氨基头孢菌素酸; 7-氨基-3-去乙酰基-头孢烷酸; 去乙酰-7-氨基头孢烷酸; 7乙酰-7-氨基头孢烷酸; 去乙酰基-7-氨基头孢烷酸; 头孢曲松钠杂质22; 脱乙酰-7-氨基头孢菌素酸头孢菌素杂质A; 头孢西酮杂质 18; 头孢他酮杂质1
• 英文别名: Intermediate of cefoselis Sulfate (7-Amino-3-(hydroxymethyl)-3-chem-4-cboxylic acid ); Cefazedone Impurity 11; 7β-Amino-3-(hydroxymethyl)cham-3-ene-4-cboxylic acid; D-7-ACA 7-HACA; Einecs -2; 3-HydroxyMethyl-7-aMinoch-3-eM-4-cboxylic Acid; 7-Amino-3-(hydroxymethyl)-chem-4-cboxylic acid; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-cboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, (6R-trans); Desacetyl-7-amino chalosporanic acid; Cefazedone Impurity 18; (6R-trans)-7-amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid; HACA/D-7-ACA; D-7-ACA; (6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylic acid; Hydroxymethyl-7-Aminocephalosporanic acid; Cefazedone Related Impurity 11; Hydroxymethyl-7-Aminochalosporanic acid //BP; 7-Aminodeacetylchalosporanic acid; Deacetyl-7-aMinochalosporanic Acid; 7-ACA-D-7ACA; 7-HACA; 7-ACA Impurity 1(-ACA); N-[2-(Dimethylamino)ethyl]acridine-4-cboxamide; 2,6/2,7-ADA; D-7-ACA,Cefazedone Impurity 11; Chalosporin impurity 1 (7-Amino-deacetylchalosporanic Acid); 7-(Phenylacetylamino)deacetylchalosporanic acid; Ceftriaxone 7-ADCA Impurity; (2S)-N-[(2S,4R)-4-acetamido-1-[[(2S)-2-[[(2R)-6-amino-2-[[(2S)-3-(4-hydroxyphenyl)-2-(methylamino)-1-oxopropyl]amino]-1-oxohexyl]amino]-4-methyl-1-oxopentyl]-[(2S)-2-[[(2R)-2-amino-1-oxo-3-(3-pyridiny; SN-22995; 7-ACA Impurity D; 7-ACA Impurity 1（Deacetyl 7-ACA）; 7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; Chalosporin iMpurity (7-Amino-deacetylchalosporanic Acid); Deacetyl 7-ACA; 7-ADACA; Hydroxymethyl-7-ACA; Ceftriaxone Impurity 22; (6R,7R)-7-Amino-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7-Amino-deacetylchalosporanicAci; 7-AMINO-3-(HYDROXYMETHYL)-3-CE; 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-cboxylicacid, 7-amino-3-(hydroxyMethyl)-8-oxo-, (6R,7R); 6R,7R)-7-Amino-3-hydroxyMethylch-3-eM-4-cboxylic Acid; Hydroxymethyl-7-Aminochalosporanic acid; 7-Amino-3-(hydrox; Chalosporin Impurity A; Chalosporin impurity 1

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 617.9±55.0 °C at 760 mmHg
• 分子式: C₈H₁₀N₂O₄S
• 分子量: 230.241
• 闪点: 327.5±31.5 °C
• 精确质量: 230.036133
• PSA: 129.16000
• LogP: -1.11
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.0±4.1 mmHg at 25°C
• 折射率: 1.743
• 储存条件: 室温，干燥

合成路线

957-68-6 ~86% 15690-38-7

文献：Singh, Santosh Kumar; Tiwari; Jain, Praveen Synthetic Communications, 2003 , vol. 33, # 14 p. 2475 - 2482

上下游产品

上游产品  1
957-68-6
下游产品  5
56271-94-4 91832-40-5 105889-45-0 153012-37-4
15686-71-2