5116-22-3

• 常用中文名：5-甲氧基甲基-2-脱氧尿苷
• 常用英文名：5-METHOXYMETHYL-2'-DEOXYURIDINE
• CAS号：5116-22-3
• 分子式：C₁₁H₁₆N₂O₆
• 分子量：272.25500
• 发布时间：2018-03-02 08:00:00
• 更新时间：2024-02-28 14:22:06

名称

• 中文名: 5-甲氧基甲基-2-脱氧尿苷
• 英文名: 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-(methoxymethyl)pyrimidine-2,4-dione
• 英文别名: 5-Methoxymethyl-2'-deoxyuridine; Uridine,2'-deoxy-5-methoxymethyl; 5-methoxymethyldeoxyuridine; MMUdR; Methoxymethyl deoxyuridine

物化性质

• 密度: 1.427g/cm3
• 分子式: C₁₁H₁₆N₂O₆
• 分子量: 272.25500
• 精确质量: 272.10100
• PSA: 113.78000
• 折射率: 1.565

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YU7900000 CHEMICAL NAME : Uridine, 2'-deoxy-5-methoxymethyl- CAS REGISTRY NUMBER : 5116-22-3 LAST UPDATED : 199712 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C11-H16-N2-O6 MOLECULAR WEIGHT : 272.29 WISWESSER LINE NOTATION : T6NVMVJ E1O1 A- ET5OTJ B1Q CQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - hamster DOSE/DURATION : 6 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 15 gm/kg/15D-I TOXIC EFFECTS : Liver - other changes Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases MUTATION DATA TYPE OF TEST : Mutation in mammalian somatic cells TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 256 mg/L REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 86,180,1986

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