3099-31-8

• 常用中文名：3-氯甲基吡啶
• 常用英文名：3-(Chloromethyl)pyridine
• CAS号：3099-31-8
• 分子式：C₆H₆ClN
• 分子量：127.572
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 甲基吡啶
• 发布时间：2018-08-27 12:08:49
• 更新时间：2025-08-25 17:59:56

名称

• 中文名: 3-氯甲基吡啶
• 英文名: 3-(chloromethyl)pyridine
• 英文别名: 3-Picolyl chloride; Nicotinyl chloride; 5-chloromethylpyridine; 3-Pyridylmethyl chloride; T6NJ C1G; α-Chloro-3-picoline; Pyridine, 3-(chloromethyl)-; 3-(Chloromethyl)pyridine; 3-Picolylchloridehydrochloride; 3-pyridinylmethyl chloride

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 210.0±15.0 °C at 760 mmHg
• 熔点: 137-143ºC
• 分子式: C₆H₆ClN
• 分子量: 127.572
• 闪点: 100.5±6.0 °C
• 精确质量: 127.018875
• PSA: 12.89000
• LogP: 1.00
• 蒸汽压: 0.3±0.4 mmHg at 25°C
• 折射率: 1.530

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : US6810000 CHEMICAL NAME : Pyridine, 3-(chloromethyl)- CAS REGISTRY NUMBER : 3099-31-8 BEILSTEIN REFERENCE NO. : 0107714 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C6-H6-Cl-N MOLECULAR WEIGHT : 127.58 WISWESSER LINE NOTATION : T6NJ C1G HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation in microorganisms TEST SYSTEM : Bacteria - Salmonella typhimurium DOSE/DURATION : 250 mg/L REFERENCE : ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 2,234,1980

安全

• 海关编码: 2933399090

合成路线

6959-48-4 ~96% 3099-31-8

文献：Bisacchi, Gregory S.; Sutton, James C.; Slusarchyk, William A.; Treuner, Uwe; Zhao, Guohua Patent: US2004/147502 A1, 2004 ; Location in patent: Page/Page column 26-27 ;

100-55-0 ~71% 3099-31-8

文献：Ojo, Babatunde Synthetic Communications, 2012 , vol. 42, # 12 p. 1731 - 1745

52761-08-7 ~% 3099-31-8

文献：Journal of the American Chemical Society, , vol. 73, p. 4925

108-99-6 ~26% 4377-33-7 3099-31-8

文献：Newkome, George R.; Kiefer, Garry E.; Yuan-Jiao Xia; Gupta, Vinod K. Synthesis, 1984 , # 8 p. 676 - 679

500-22-1 ~% 3099-31-8

文献：ACS Medicinal Chemistry Letters, , vol. 4, # 2 p. 278 - 282

上下游产品

上游产品  5
6959-48-4 100-55-0 52761-08-7 108-99-6
500-22-1
下游产品  10
39244-80-9 2682-86-2 108-99-6 100553-75-1
35854-44-5 150378-17-9 118001-72-2 74095-34-4
82401-08-9 851761-78-9

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%