866546-11-4

• 常用中文名：5-氯-3-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1-甲苯磺酰-1H-吡咯并[2,3-B]吡啶
• 常用英文名：5-CHLORO-3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)-1-TOSYL-1H-PYRROLO[2,3-B]PYRIDINE
• CAS号：866546-11-4
• 分子式：C₂₀H₂₂BClN₂O₄S
• 分子量：432.729
• 发布时间：2018-10-16 16:57:33
• 更新时间：2025-08-25 23:36:12

名称

• 中文名: 5-氯-3-(4,4,5,5-四甲基-1,3,2-二噁硼烷-2-基)-1-甲苯磺酰-1H-吡咯并[2,3-b]吡啶
• 英文名: 5-chloro-1-(4-methylphenyl)sulfonyl-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolo[2,3-b]pyridine
• 英文别名: 1H-Pyrrolo[2,3-b]pyridine, 5-chloro-1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 5-chloro-1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3.2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]-pyridine; 5-chloro-3-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-1-(toluene-4-sulfonyl)-1H-[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine,5-chloro-1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl); 5-chloro-3-(4,4,5,5-tetramethyl-1,3.2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrolo[2,3-b]-pyridine; 5-chloro-1-(p-tolylsulfonyl)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrolo[2,3-b]pyridine; 5-Chloro-1-[(4-methylphenyl)sulfonyl]-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrolo[2,3-b]pyridine; 5-Chloro-1-tosyl-7-azaindole-3-boronic acid pinacol ester

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 584.5±60.0 °C at 760 mmHg
• 分子式: C₂₀H₂₂BClN₂O₄S
• 分子量: 432.729
• 闪点: 307.3±32.9 °C
• 精确质量: 432.108185
• PSA: 78.80000
• LogP: 4.61510
• 蒸汽压: 0.0±1.6 mmHg at 25°C
• 折射率: 1.605
• 储存条件: 2~8℃

合成路线

866546-10-3 73183-34-3 ~50% 866546-11-4

文献：VERTEX PHARMACEUTICALS INCORPORATED? Patent: WO2005/95400 A1, 2005 ; Location in patent: Page/Page column 345; 348 ; WO 2005/095400 A1

1072-98-6 ~% 866546-11-4

文献：MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

211308-81-5 ~% 866546-11-4

文献：MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

866318-90-3 ~% 866546-11-4

文献：MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

866546-09-0 ~% 866546-11-4

文献：MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

866546-07-8 ~% 866546-11-4

文献：MERCK SHARP and DOHME CORP.; CASH, Brandon; FISCHER, Christian; GARCIA, Yudith; JUNG, Joon; KATZ, Jason; KIM, June; RIVKIN, Alexey; SCHELL, Adam; SIU, Tony; WITTER, David; ZHOU, Hua Patent: WO2011/137022 A1, 2011 ;

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