882562-40-5

• 常用中文名：3-(2,5-二氯嘧啶-4-基)-1-(苯基磺酰基)-1H-吲哚
• 常用英文名：3-(2,5-Dichloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole
• CAS号：882562-40-5
• 分子式：C₁₈H₁₁Cl₂N₃O₂S
• 分子量：404.270
• 发布时间：2018-12-26 07:11:05
• 更新时间：2024-01-12 15:22:27

名称

• 中文名: 3-(2,5-二氯嘧啶-4-基)-1-(苯基磺酰基)-1H-吲哚
• 英文名: 3-(2,5-Dichloropyrimidin-4-yl)-1-(phenylsulfonyl)-1H-indole
• 英文别名: 1H-Indole, 3-(2,5-dichloro-4-pyrimidinyl)-1-(phenylsulfonyl)-; 1-(benzenesulfonyl)-3-(2,5-dichloropyrimidin-4-yl)indole; 3-(2,5-Dichloro-4-pyrimidinyl)-1-(phenylsulfonyl)-1H-indole

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 650.4±65.0 °C at 760 mmHg
• 分子式: C₁₈H₁₁Cl₂N₃O₂S
• 分子量: 404.270
• 闪点: 347.1±34.3 °C
• 精确质量: 402.994904
• PSA: 73.23000
• LogP: 4.47
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.709
• 储存条件: 2-8°C，保存于惰性气体中

安全

• 海关编码: 2933990090

合成路线

5750-76-5 129271-98-3 ~90% 882562-40-5

文献：CELLTECH R and D LIMITED Patent: WO2006/38001 A1, 2006 ; Location in patent: Page/Page column 40 ; WO 2006/038001 A1

937366-57-9 98-09-9 ~47% 882562-40-5

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BUTTERWORTH, Sam; FINLAY, Maurice, Raymond, Verschoyle; WARD, Richard, Andrew; KADAMBAR, Vasantha, Krishna; CHANDRASHEKAR, Reddy, C.; MURUGAN, Andiappan; REDFEARN, Heather, Marie Patent: WO2013/14448 A1, 2013 ; Location in patent: Page/Page column 88; 89 ; WO 2013/014448 A1

870717-93-4 5750-76-5 ~66% 882562-40-5

文献：Ward, Richard A.; Anderton, Mark J.; Ashton, Susan; Bethel, Paul A.; Box, Matthew; Butterworth, Sam; Colclough, Nicola; Chorley, Christopher G.; Chuaqui, Claudio; Cross, Darren A.E.; Dakin, Les A.; Debreczeni, Judit E.; Eberlein, Cath; Finlay, M. Raymond V.; Hill, George B.; Grist, Matthew; Klinowska, Teresa C.M.; Lane, Clare; Martin, Scott; Orme, Jonathon P.; Smith, Peter; Wang, Fengjiang; Waring, Michael J. Journal of Medicinal Chemistry, 2013 , vol. 56, # 17 p. 7025 - 7048

120-72-9 ~% 882562-40-5

文献：ASTRAZENECA AB; ASTRAZENECA UK LIMITED; BUTTERWORTH, Sam; FINLAY, Maurice, Raymond, Verschoyle; WARD, Richard, Andrew; KADAMBAR, Vasantha, Krishna; CHANDRASHEKAR, Reddy, C.; MURUGAN, Andiappan; REDFEARN, Heather, Marie Patent: WO2013/14448 A1, 2013 ; WO 2013/014448 A1

上下游产品

上游产品  6
5750-76-5 129271-98-3 937366-57-9 98-09-9
870717-93-4 120-72-9
下游产品  1
937366-57-9

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%