118283-03-7

• 常用中文名：(R)-1-(苄基氨基)-4-甲基-1-氧代-2-戊基氨基甲酸叔丁酯
• 常用英文名：tert-butyl N-[1-(benzylamino)-4-methyl-1-oxopentan-2-yl]carbamate
• CAS号：118283-03-7
• 分子式：C₁₈H₂₈N₂O₃
• 分子量：320.42700
• 发布时间：2018-11-30 17:49:38
• 更新时间：2025-08-25 19:33:04

名称

• 中文名: (R)-1-(苄基氨基)-4-甲基-1-氧代-2-戊基氨基甲酸叔丁酯
• 英文名: tert-butyl N-[1-(benzylamino)-4-methyl-1-oxopentan-2-yl]carbamate
• 英文别名: 1-benzyloxycarbamoyl-3-methyl-butyl-carbamic acid tert-butyl ester; N-tert-butoxycarbonyl-L-leucine benzylamide

物化性质

• 分子式: C₁₈H₂₈N₂O₃
• 分子量: 320.42700
• 精确质量: 320.21000
• PSA: 74.41000
• LogP: 4.28690

合成路线

13139-15-6 100-46-9 ~80% 118283-03-7

文献：MEDIVIR AB Patent: WO2008/107365 A1, 2008 ; Location in patent: Page/Page column 63 ; WO 2008/107365 A1

13139-15-6 ~% 118283-03-7

文献：Girodano; Gallina; Ottaviano; Consalvi; Scandurra European Journal of Medicinal Chemistry, 1992 , vol. 27, # 9 p. 865 - 873

63096-02-6 100-46-9 ~80% 118283-03-7

文献：Ohshima, Takashi; Hayashi, Yukiko; Agura, Kazushi; Fujii, Yuka; Yoshiyama, Asako; Mashima, Kazushi Chemical Communications, 2012 , vol. 48, # 44 p. 5434 - 5436

3392-09-4 100-46-9 ~66% 118283-03-7

文献：Postnikova, Brenda J.; Anslyn, Eric V. Tetrahedron Letters, 2004 , vol. 45, # 3 p. 501 - 504

87746-56-3 100-46-9 ~% 118283-03-7

文献：Nadimpally, Krishna Chaitanya; Thalluri, Kishore; Palakurthy, Nani Babu; Saha, Abhijit; Mandal, Bhubaneswar Tetrahedron Letters, 2011 , vol. 52, # 20 p. 2579 - 2582

3392-09-4 3287-99-8 ~% 118283-03-7

文献：DeSolms; Giuliani; Guare; Vacca; Sanders; Graham; Wiggins; Darke; Sigal; Zugay; Emini; Schleif; Quintero; Anderson; Huff Journal of Medicinal Chemistry, 1991 , vol. 34, # 9 p. 2852 - 2857

66866-44-2 100-46-9 ~% 118283-03-7

文献：Girodano; Gallina; Ottaviano; Consalvi; Scandurra European Journal of Medicinal Chemistry, 1992 , vol. 27, # 9 p. 865 - 873

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