55477-20-8

• 常用中文名：4-Chloro-2-(tert-butylamino)-6-(4-methylpiperazino)-5-(methylthio)pyrimidine
• 常用英文名：4-Chloro-2-(tert-butylamino)-6-(4-methylpiperazino)-5-(methylthio)pyrimidine
• CAS号：55477-20-8
• 分子式：C₁₄H₂₄ClN₅S
• 分子量：329.89200
• 发布时间：2016-10-28 02:56:03
• 更新时间：2024-04-03 14:12:14

名称

• 英文名: N-tert-butyl-4-chloro-6-(4-methylpiperazin-1-yl)-5-methylsulfanylpyrimidin-2-amine
• 英文别名: 2-tert-Butylamino-4-N-methylpiperazino-5-methylthio-6-chloro-pyrimidine; 4-Chloro-2-(tert-butylamino)-6-(4-methylpiperazino)-5-methylthiopyrimidine; tert-butyl-[4-chloro-6-(4-methyl-piperazin-1-yl)-5-methylsulfanyl-pyrimidin-2-yl]-amine; Pyrimidine,4-chloro-2-(tert-butylamino)-6-(4-methylpiperazino)-5-methylthio; 2-tert-Butylamino-4-(4-methylpiperazino)-5-methylmercapto-6-chlorpyrimidin

物化性质

• 密度: 1.23g/cm3
• 沸点: 459.5ºC at 760 mmHg
• 分子式: C₁₄H₂₄ClN₅S
• 分子量: 329.89200
• 闪点: 231.7ºC
• 精确质量: 329.14400
• PSA: 69.59000
• LogP: 2.89000
• 折射率: 1.598
• 储存条件: 库房低温通风干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UV7910000 CHEMICAL NAME : Pyrimidine, 4-chloro-2-(tert-butylamino)-6-(4-methylpiperazino)-5 -methylthio- CAS REGISTRY NUMBER : 55477-20-8 BEILSTEIN REFERENCE NO. : 0889233 LAST UPDATED : 199703 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C14-H24-Cl-N5-S MOLECULAR WEIGHT : 329.94 WISWESSER LINE NOTATION : T6N DNTJ A1 D- DT6N CNJ BMX1&1&1 ES1 FG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,553,1975 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 67 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,553,1975