80937-24-2

• 常用中文名：(E)-4-(2-Nitrophenyl)-4-oxo-2-butenoic acid
• 常用英文名：(E)-4-(2-Nitrophenyl)-4-oxo-2-butenoic acid
• CAS号：80937-24-2
• 分子式：C₁₀H₇NO₅
• 分子量：221.16600
• 发布时间：2017-03-16 18:48:10
• 更新时间：2025-08-26 00:47:45

名称

• 英文名: (2E)-4-(2-Nitrophenyl)-4-oxo-2-butenoic acid
• 英文别名: Hydroxydehydro Nifedipine Carboxylate

物化性质

• 密度: 1.435g/cm3
• 沸点: 437.4ºC at 760 mmHg
• 分子式: C₁₀H₇NO₅
• 分子量: 221.16600
• 闪点: 193.3ºC
• 精确质量: 221.03200
• PSA: 100.19000
• LogP: 1.94150
• 折射率: 1.614

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : EM9259000 CHEMICAL NAME : 2-Butenoic acid, 4-(2-nitrophenyl)-4-oxo-, (E)- CAS REGISTRY NUMBER : 80937-24-2 LAST UPDATED : 199609 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C10-H7-N-O5 MOLECULAR WEIGHT : 221.18 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2481118

合成路线

577-59-3 298-12-4 ~79% 80937-24-2

文献：Chakor, Narayan; Dallavalle, Sabrina; Musso, Loana; Moretti, Maddalena Tetrahedron Letters, 2008 , vol. 49, # 34 p. 5056 - 5058

577-59-3 563-96-2 ~42% 80937-24-2

文献：Bianchi, Mario; Butti, Alina; Christidis, Yani; Perronnet, Jacques; Barzaghi, Fernando; et al. European Journal of Medicinal Chemistry, 1988 , vol. 23, p. 45 - 52

141-82-2 58950-89-3 ~% 80937-24-2

文献：Steinbach; Becker Journal of the American Chemical Society, 1954 , vol. 76, p. 5808 Full Text View citing articles Show Details Sato; Ohta Bulletin of the Chemical Society of Japan, 1955 , vol. 28, p. 480

577-59-3 ~% 80937-24-2

文献：Sato; Ohta Bulletin of the Chemical Society of Japan, 1955 , vol. 28, p. 480