143407-75-4

• 常用中文名：sodium,(6R,7R)-7-[[1-(4-bromophenyl)cyclopentanecarbonyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• 常用英文名：sodium,(6R,7R)-7-[[1-(4-bromophenyl)cyclopentanecarbonyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• CAS号：143407-75-4
• 分子式：C₂₀H₂₀BrN₂NaO₄S
• 分子量：487.34300
• 发布时间：2016-04-02 04:22:47
• 更新时间：2024-04-01 23:25:11

名称

• 英文名: sodium,(6R,7R)-7-[[1-(4-bromophenyl)cyclopentanecarbonyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate

物化性质

• 沸点: 745.3ºC at 760mmHg
• 分子式: C₂₀H₂₀BrN₂NaO₄S
• 分子量: 487.34300
• 闪点: 404.5ºC
• 精确质量: 486.02200
• PSA: 118.33000
• LogP: 2.46290
• 蒸汽压: 2.5E-23mmHg at 25°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XI0369150 CHEMICAL NAME : 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-(((1-(4-bromophenyl)cyclopentyl) carbonyl)amino)-3-methyl-8-oxo-, monosodium salt, (6R-trans)- CAS REGISTRY NUMBER : 143407-75-4 LAST UPDATED : 199409 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C20-H20-Br-N2-O4-S.Na MOLECULAR WEIGHT : 487.38 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 26,169,1992

合成路线

22252-43-3 143328-29-4 ~47% 143407-75-4

文献：Mndzhoyan, Sh. L.; Kramer, M. S.; Akopyan, S. G.; Grigoryan, M. M.; Ter-Zakharyan, Yu. Z.; et al. Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 2 p. 169 - 173 Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 2 p. 54 - 56

16532-79-9 ~% 143407-75-4

文献：Mndzhoyan, Sh. L.; Kramer, M. S.; Akopyan, S. G.; Grigoryan, M. M.; Ter-Zakharyan, Yu. Z.; et al. Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 2 p. 169 - 173 Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 2 p. 54 - 56

143328-19-2 ~% 143407-75-4

文献：Mndzhoyan, Sh. L.; Kramer, M. S.; Akopyan, S. G.; Grigoryan, M. M.; Ter-Zakharyan, Yu. Z.; et al. Pharmaceutical Chemistry Journal, 1992 , vol. 26, # 2 p. 169 - 173 Khimiko-Farmatsevticheskii Zhurnal, 1992 , vol. 26, # 2 p. 54 - 56