101987-76-2

• 常用中文名：3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-
• 常用英文名：3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-Methyl-1-piperazinyl)-4-oxo-
• CAS号：101987-76-2
• 分子式：C₁₈H₁₉ClFN₃O₃
• 分子量：379.81300
• 发布时间：2017-11-10 07:41:12
• 更新时间：2025-08-31 20:49:26

名称

• 英文名: 8-chloro-1-cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• 英文别名: 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 3-Quinolinecarboxylicacid,8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-(3-methyl-1-piperazinyl)-4-oxo; 8-chloro-1-cyclopropyl-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

物化性质

• 密度: 1.468g/cm3
• 沸点: 598.3ºC at 760mmHg
• 分子式: C₁₈H₁₉ClFN₃O₃
• 分子量: 379.81300
• 闪点: 315.7ºC
• 精确质量: 379.11000
• PSA: 74.57000
• LogP: 3.01900
• 蒸汽压: 3.65E-15mmHg at 25°C
• 折射率: 1.637

合成路线

109-07-9 101987-89-7 ~30% 101987-76-2

文献：Domagala; Bridges; Culbertson; Gambino; Hagen; Karrick; Porter; Sanchez; Sesnie; Spense; Szotek; Wemple Journal of Medicinal Chemistry, 1991 , vol. 34, # 3 p. 1142 - 1154