327623-37-0

• 常用中文名：(2S,3r)-2-((s)-1-(3,5-双(三氟甲基)苯基)乙氧基)-3-(4-氟苯基)吗啉
• 常用英文名：(2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)Morpholine
• CAS号：327623-37-0
• 分子式：C₂₀H₁₈F₇NO₂
• 分子量：437.35100
• 发布时间：2019-01-12 15:45:22
• 更新时间：2025-09-14 19:17:28

名称

• 中文名: (2S,3r)-2-((s)-1-(3,5-双(三氟甲基)苯基)乙氧基)-3-(4-氟苯基)吗啉
• 英文名: (2S,3R)-2-[(1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholine
• 中文别名: (2S,3R)-2-[(1S)-1-[3,5-双(三氟甲基)苯基]乙氧基]-3-(4-氟苯基)吗啉盐酸盐
• 英文别名: (2R,3S)-2-{(1R)-1-[3,5-bis-trifluoromethylphenyl]ethoxy}-3-(4-fluorophenyl)morpholine; (2S,3R)-2-[(1S)-1-(3,5-bis-trifluoro-methylphenyl)ethoxy]-3-(4-fluorophenyl)morpholine; QC-634; (2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholine; 2s,3r------s; Aprepitant Impurity 10

物化性质

• 分子式: C₂₀H₁₈F₇NO₂
• 分子量: 437.35100
• 精确质量: 437.12300
• PSA: 30.49000
• LogP: 5.95690

合成路线

934540-47-3 ~% 327623-37-0 171338-27-5

文献：DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC. Patent: WO2007/44829 A2, 2007 ; Location in patent: Page/Page column 43 ;

1523569-83-6 ~% 1185503-48-3 327623-37-0

文献：Wan, Wei-Li; He, Yun; Guan, Mei; Li, Xiao-Long; Cheng, Xu; Wu, Yong Chinese Chemical Letters, 2013 , vol. 24, # 12 p. 1118 - 1122

1523569-82-5 ~% 327623-37-0

文献：Wan, Wei-Li; He, Yun; Guan, Mei; Li, Xiao-Long; Cheng, Xu; Wu, Yong Chinese Chemical Letters, 2013 , vol. 24, # 12 p. 1118 - 1122

403-42-9 ~% 327623-37-0

文献：Wan, Wei-Li; He, Yun; Guan, Mei; Li, Xiao-Long; Cheng, Xu; Wu, Yong Chinese Chemical Letters, 2013 , vol. 24, # 12 p. 1118 - 1122

447-43-8 ~% 327623-37-0

文献：Wan, Wei-Li; He, Yun; Guan, Mei; Li, Xiao-Long; Cheng, Xu; Wu, Yong Chinese Chemical Letters, 2013 , vol. 24, # 12 p. 1118 - 1122

上下游产品

上游产品  3
1523569-82-5 403-42-9 447-43-8
下游产品  1
172822-29-6