379228-57-6

• 常用中文名：2-氨基-4,6-二氟苯甲酸甲酯
• 常用英文名：Methyl 2-amino-4,6-difluorobenzoate
• CAS号：379228-57-6
• 分子式：C₈H₇F₂NO₂
• 分子量：187.14300
• 发布时间：2018-12-24 11:09:50
• 更新时间：2024-01-14 11:19:48

名称

• 中文名: 2-氨基-4,6-二氟苯甲酸甲酯
• 英文名: Methyl 2-amino-4,6-difluorobenzoate
• 中文别名: 2,4-二氟-6-氨基苯甲酸甲酯
• 英文别名: Benzoic acid,2-amino-4,6-difluoro-,methyl ester

物化性质

• 密度: 1.355±0.06 g/cm3
• 沸点: 266.1±40.0 ºC (760 Torr)
• 分子式: C₈H₇F₂NO₂
• 分子量: 187.14300
• 闪点: 114.7±27.3 ºC
• 精确质量: 187.04400
• PSA: 52.32000
• LogP: 1.91480
• 储存条件: 室温
• 水溶解性: Very slightly soluble (0.15 g/L) (25 ºC)

合成路线

126674-77-9 67-56-1 ~86% 379228-57-6

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

126674-77-9 77-78-1 ~66% 379228-57-6

文献：Ford, J. Gair; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Baum, John; Chubb, Richard; Fieldhouse, Robin; Muxworthy, James; Nivlet, Alex; Stenson, Rachel; Warwick, Eleanor Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1078 - 1087

126674-93-9 ~% 379228-57-6

文献：Hennequin, Laurent F.; Allen, Jack; Breed, Jason; Curwen, Jon; Fennell, Michael; Green, Tim P.; Lambert-Van Der Brempt, Christine; Morgentin, Remy; Norman, Richard A.; Olivier, Annie; Otterbein, Ludovic; Ple, Patrick A.; Warin, Nicolas; Costello, Gerard Journal of Medicinal Chemistry, 2006 , vol. 49, # 22 p. 6465 - 6488

372-39-4 ~% 379228-57-6

文献：Ford, J. Gair; Pointon, Simon M.; Powell, Lyn; Siedlecki, Paul S.; Baum, John; Chubb, Richard; Fieldhouse, Robin; Muxworthy, James; Nivlet, Alex; Stenson, Rachel; Warwick, Eleanor Organic Process Research and Development, 2010 , vol. 14, # 5 p. 1078 - 1087

上下游产品

上游产品  5
126674-77-9 67-56-1 77-78-1 126674-93-9
372-39-4
下游产品  1
379228-33-8