565-36-6

• 常用中文名：Benzenesulfonamide,3-amino-N-(5-chloro-2-pyrimidinyl)-
• 常用英文名：Benzenesulfonamide,3-amino-N-(5-chloro-2-pyrimidinyl)-
• CAS号：565-36-6
• 分子式：C₁₀H₉ClN₄O₂S
• 分子量：284.72200
• 发布时间：2017-11-20 03:25:53
• 更新时间：2024-09-15 11:42:56

名称

• 英文名: Benzenesulfonamide,3-amino-N-(5-chloro-2-pyrimidinyl)
• 英文别名: Metachloridine; WR-6010; 3-amino-N-5-chloropyrimidin-2-ylbenzenesulphonamide

物化性质

• 密度: 1.588g/cm3
• 沸点: 554.9ºC at 760mmHg
• 分子式: C₁₀H₉ClN₄O₂S
• 分子量: 284.72200
• 闪点: 289.4ºC
• 精确质量: 284.01300
• PSA: 106.35000
• LogP: 3.24800
• 折射率: 1.683

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : OY2210000 CHEMICAL NAME : Metanilamide, N'-(5-chloro-2-pyrimidyl)- CAS REGISTRY NUMBER : 565-36-6 BEILSTEIN REFERENCE NO. : 0261399 LAST UPDATED : 199709 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C10-H9-Cl-N4-O2-S MOLECULAR WEIGHT : 284.74 WISWESSER LINE NOTATION : T6N CNJ BMSWR CZ& EG HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 13,289,1968 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 700 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,469,1971 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - dog DOSE/DURATION : 100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 18,469,1971 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 1083 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CHTHBK Chemotherapy (Basel). (S. Karger Pub., Inc., 79 Fifth Ave., New York, NY 10003) V.13- 1968- Volume(issue)/page/year: 13,289,1968

合成路线

860515-70-4 ~% 565-36-6

文献：Am.Cyanamid Co. Patent: US2506351 , 1945 ; Full Text Show Details English et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 1039,1040, 1044

1950-73-8 ~% 565-36-6

文献：English et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 1039,1040, 1044

771576-51-3 ~% 565-36-6

文献：English et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 1039,1040, 1044

121-51-7 ~% 565-36-6

文献：English et al. Journal of the American Chemical Society, 1946 , vol. 68, p. 1039,1040, 1044

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