103335-41-7

• 常用中文名：非那雄胺中间体
• 常用英文名：Methyl 3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxylate
• CAS号：103335-41-7
• 分子式：C₂₀H₂₉NO₃
• 分子量：331.449
• 发布时间：2019-01-01 20:06:43
• 更新时间：2025-08-21 09:48:05

名称

• 中文名: 4-氮杂-5alpha-雄甾-1-烯-3-酮-17beta-羧酸甲酯
• 英文名: methyl (1S,3aS,3bS,5aR,9aR,9bS,11aS)-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxylate
• 中文别名: 3-氧代-4-氮杂-5alpha-雄甾-1-烯-17beta-羧酸甲酯; 非那雄胺中间体
• 英文别名: Methyl 4-aza-5alpha-Androsta-1-en-3-one-17beta-Carboxylate; 1H-Indeno[5,4-f]quinoline-7-carboxylic acid, 2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, methyl ester, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-; Methyl 3-oxo-4-aza-5a-androst-1-ene-17beta-carboxylate; Methyl 4-aza-5a-Androsta-1-en-3-one-17b-Carboxylate; 3-Oxo-4-aza-5Alpha-Alphandrost-1-ene-17Beta-carboxylic Acid Methyl Ester; (4aR,4bS,6aS,7S,9aS,9bS,11aR)-methyl 4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate; Methyl (4aR,4bS,6aS,7S,9aS,9bS,11aR)-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxylate; Methyl 3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxylate; Dutasteride Impurity 3

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 478.6±45.0 °C at 760 mmHg
• 熔点: 280-282ºC (dec.)
• 分子式: C₂₀H₂₉NO₃
• 分子量: 331.449
• 闪点: 243.3±28.7 °C
• 精确质量: 331.214752
• PSA: 55.40000
• LogP: 3.24
• 外观性状: 灰白色固体
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.525
• 储存条件: 2-8°C，干燥

合成路线

73671-92-8 ~% 103335-41-7

文献：Journal of the American Chemical Society, , vol. 110, # 10 p. 3318 - 3319

上下游产品

上游产品  1
73671-92-8
下游产品  2
98319-26-7 104239-97-6