942145-77-9

• 常用中文名：1,2,3,6-四氢-1,1-二甲基-氮杂卓酮[4,5-B]吲哚-5-羧酸-1-甲基乙酯
• 常用英文名：ISOPROPYL 1,1-DIMETHYL-1,2,3,6-TETRAHYDROAZEPINO[4,5-B]INDOLE-5-CARBOXYLATE
• CAS号：942145-77-9
• 分子式：C₁₈H₂₂N₂O₂
• 分子量：298.37900
• 发布时间：2018-12-18 13:05:27
• 更新时间：2024-01-31 14:38:48

名称

• 中文名: 1,2,3,6-四氢-1,1-二甲基-氮杂卓酮[4,5-B]吲哚-5-羧酸-1-甲基乙酯
• 英文名: propan-2-yl 1,1-dimethyl-3,6-dihydro-2H-azepino[4,5-b]indole-5-carboxylate
• 英文别名: isopropyl 1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate; 1-methylethyl 1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate; Azepino[4,5-b]indole-5-carboxylic acid,1,2,3,6-tetrahydro-1,1-dimethyl-,1-methylethyl ester; (E)-isopropyl 1,1-dimethyl-1,2,3,6-tetrahydroazepino[4,5-b]indole-5-carboxylate

物化性质

• 密度: 1.133g/cm3
• 沸点: 492.3ºC at 760 mmHg
• 分子式: C₁₈H₂₂N₂O₂
• 分子量: 298.37900
• 闪点: 251.5ºC
• 精确质量: 298.16800
• PSA: 54.12000
• LogP: 3.67000
• 折射率: 1.581
• 储存条件: 2-8°C

安全

• 海关编码: 2933990090

合成路线

1227748-44-8 1227748-49-3 ~% 942145-77-9

文献：EXELIXIS, INC. Patent: WO2007/70796 A1, 2007 ; Location in patent: Page/Page column 110; 116; 119 ; WO 2007/070796 A1

56417-63-1 15467-31-9 ~% 942145-77-9

文献：Flatt, Brenton; Martin, Richard; Wang, Tie-Lin; Mahaney, Paige; Murphy, Brett; Gu, Xiao-Hui; Foster, Paul; Li, Jiali; Pircher, Parinaz; Petrowski, Mary; Schulman, Ira; Westin, Stefan; Wrobel, Jay; Yan, Grace; Bischoff, Eric; Daige, Chris; Mohan, Raju Journal of Medicinal Chemistry, 2009 , vol. 52, # 4 p. 904 - 907

上下游产品

上游产品  3
1227748-44-8 56417-63-1 15467-31-9
下游产品  1
629664-81-9

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%