5919-29-9

• 常用中文名：乙基 2-(乙酰基氨基)-4,5,6,7-四氢-1-苯并噻吩-3-羧酸
• 常用英文名：Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-2-(acetylamino)-, ethyl ester
• CAS号：5919-29-9
• 分子式：C₁₃H₁₇NO₃S
• 分子量：267.34400
• 发布时间：2018-12-25 11:51:57
• 更新时间：2025-08-28 00:54:48

名称

• 中文名: 乙基 2-(乙酰基氨基)-4,5,6,7-四氢-1-苯并噻吩-3-羧酸
• 英文名: ethyl 2-acetamido-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate
• 中文别名: 2-乙酰氨基-4,5,6,7-四氢苯并噻吩-3-甲酸乙酯; 2-乙酰氨基-4,5,6,7-四氢苯并[B]噻吩-3-甲酸 乙酯; 2-乙酰氨基-4,5,6,7-四氢-1-苯并噻吩-3-羧酸乙酯; 2-(乙酰基氨基)-4,5,6,7-四氢-1-苯并噻吩-3-甲酸乙酯; 2-乙酰氨基-4,5,6,7-四氢苯并噻吩-3-羧酸乙酯; 2-乙酰氨基-4,5,6,7-四氢-1-苯并噻吩-3-甲酸乙酯
• 英文别名: ethyl 2-(acetylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxylate; Benzo[b]thiophene-3-cboxylic acid, 2-(acetylamino)-4,5,6,7-tetrahydro-, ethyl ester; ethyl 2-acetamido-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; 2-acetamido-4,5,6,7-tetrahydrobenzothiophene-3-cboxylic acid ethyl ester; ETHYL 2-ACETAMIDO-4,5,6,7-TETRAHYDROBENZO[B]THIOPHENE-3-CBOXYLATE; Ethyl 4,5,6,7-tetrahydro-2-(acetylamino)benzo(b)thiophene-3-cboxylate; 2-Acetylamino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-carboxylic acid ethyl ester; ethyl 2-acetamido-4,5,6,7-tetrahydrobenzothiophene-3-cboxylate; Benzo(b)thiophene-3-carboxylic acid,4,5,6,7-tetrahydro-2-(acetylamino)-,ethyl ester; 2-acetamido-3-carboethoxy-4,5-tetramethylenethiophene; 2-ACETYLAMINO-4,5,6,7-TETRAHYDRO-BENZO[B]THIOPHENE-3-CBOXYLIC ACID ETHYL ESTER; Ethyl 4,5,6,7-tetrahydro-2-(acetylamino)benzo(b)thiophene-3-carboxylate; IFLAB-BB F0863-0548; ethyl 2-(acetylamino)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate; Benzo(b)thiophene-3-cboxylic acid, 4,5,6,7-tetrahydro-2-(acetylamino)-, ethyl ester; TIMTEC-BB SBB001041; ethyl 2-acetamido-4,5,6,7-tetrahydro-1-benzothiophene-3-cboxylate; 2-acetylamino-4,5,6,7-tetrahydrobenzothiophene-3-carboxylic acid ethyl ester; AURORA

物化性质

• 密度: 1.253g/cm3
• 沸点: 492.9ºC at 760 mmHg
• 分子式: C₁₃H₁₇NO₃S
• 分子量: 267.34400
• 闪点: 251.9ºC
• 精确质量: 267.09300
• PSA: 83.64000
• LogP: 2.83500
• 折射率: 1.591

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DL9603600 CHEMICAL NAME : Benzo(b)thiophene-3-carboxylic acid, 4,5,6,7-tetrahydro-2-(acetylamino)-, ethyl ester CAS REGISTRY NUMBER : 5919-29-9 BEILSTEIN REFERENCE NO. : 1318072 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C13-H17-N-O3-S MOLECULAR WEIGHT : 267.37 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1 gm/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - ptosis Behavioral - changes in motor activity (specific assay) Lungs, Thorax, or Respiration - respiratory depression REFERENCE : EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 15,413,1980

安全

• 海关编码: 2934999090

合成路线

4506-71-2 75-36-5 ~97% 5919-29-9

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2003/104219 A1, 2003 ; Location in patent: Page 10; 12 ; WO 03/104219 A1

4506-71-2 108-24-7 ~97% 5919-29-9

文献：Aurelio, Luigi; Flynn, Bernard L.; Scammells, Peter J. Organic and Biomolecular Chemistry, 2011 , vol. 9, # 13 p. 4886 - 4902

4506-71-2 ~% 5919-29-9

文献：US2005/176742 A1, ;

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%