CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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MB8210000
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CHEMICAL NAME :
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Glycine, N,N-bis(2-(bis(carboxymethyl)amino)ethyl)-, calcium trisodium salt
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CAS REGISTRY NUMBER :
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12111-24-9
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LAST UPDATED :
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199701
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DATA ITEMS CITED :
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13
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MOLECULAR FORMULA :
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C14-H18-N3-O10.Ca.3Na
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MOLECULAR WEIGHT :
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497.40
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WISWESSER LINE NOTATION :
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OV1N1VO&2N1VO2N1VO&1VO &-NA- 3 &-CA-
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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2512 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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7269 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intraperitoneal
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DOSE :
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659 mg/kg
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SEX/DURATION :
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female 9 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - eye/ear Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain)
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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1790 mg/kg
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SEX/DURATION :
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female 9-13 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - Central Nervous System
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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2685 mg/kg
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SEX/DURATION :
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female 9-13 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - eye/ear
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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3581 mg/kg
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SEX/DURATION :
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female 7-11 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Specific Developmental Abnormalities - Central Nervous System Reproductive - Specific Developmental Abnormalities - eye/ear
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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30 gm/kg
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SEX/DURATION :
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female 1-21 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Subcutaneous
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DOSE :
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3580 mg/kg
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SEX/DURATION :
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female 7-11 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Fertility - abortion
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TYPE OF TEST :
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DNA inhibition
MUTATION DATA
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TYPE OF TEST :
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Mutation test systems - not otherwise specified
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TEST SYSTEM :
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Rodent - rat Liver
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DOSE/DURATION :
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10 mmol/L
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REFERENCE :
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BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 23,901,1974 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9954 No. of Facilities: 116 (estimated) No. of Industries: 1 No. of Occupations: 4 No. of Employees: 1702 (estimated) No. of Female Employees: 1258 (estimated)
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