1476-33-1

• 常用中文名：3-(2-(二甲基氨基)乙基)-3-吲哚-6-醇
• 常用英文名：3-[2-(Dimethylamino)ethyl]-1H-indol-6-ol
• CAS号：1476-33-1
• 分子式：C₁₂H₁₆N₂O
• 分子量：204.26800
• 发布时间：2018-12-25 08:57:21
• 更新时间：2023-02-01 12:05:09

名称

• 中文名: 3-(2-(二甲基氨基)乙基)-3-吲哚-6-醇
• 英文名: 3-[2-(Dimethylamino)ethyl]-1H-indol-6-ol
• 英文别名: 6-Hydroxy-dimethyltryptamin; 6-Hydroxy-N,N-dimethyltryptamin; 6-Hydroxy-N,N-dimethyltryptamine

物化性质

• 密度: 1.178g/cm3
• 沸点: 392.8ºC at 760mmHg
• 分子式: C₁₂H₁₆N₂O
• 分子量: 204.26800
• 闪点: 191.3ºC
• 精确质量: 204.12600
• PSA: 39.26000
• LogP: 1.97760
• 蒸汽压: 9.89E-07mmHg at 25°C
• 折射率: 1.646

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NM2975000 CHEMICAL NAME : Indol-6-ol, 3-(2-(dimethylamino)ethyl)- CAS REGISTRY NUMBER : 1476-33-1 BEILSTEIN REFERENCE NO. : 0160817 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C12-H16-N2-O MOLECULAR WEIGHT : 204.30 WISWESSER LINE NOTATION : T56 BMJ D2N1&1 HQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Human - man DOSE/DURATION : 1 mg/kg TOXIC EFFECTS : Behavioral - changes in motor activity (specific assay) Vascular - BP elevation not characterized in autonomic section REFERENCE : PSYPAG Psychopharmacologia (Berlin). (Berlin, Ger.) V.1-46, 1959-76. For publisher information, see PSCHDL. Volume(issue)/page/year: 4,39,1963

合成路线

94308-66-4 ~% 1476-33-1

文献：Furman, Svetlana; Nissim-Bardugo, Elinor; Zeeli, Shani; Weitman, Michal; Nudelman, Abraham; Finkin-Groner, Efrat; Moradov, Dorit; Shifrin, Helena; Schorer-Apelbaum, Donna; Weinstock, Marta Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 10 p. 2283 - 2287

130955-91-8 ~% 1476-33-1

文献：Furman, Svetlana; Nissim-Bardugo, Elinor; Zeeli, Shani; Weitman, Michal; Nudelman, Abraham; Finkin-Groner, Efrat; Moradov, Dorit; Shifrin, Helena; Schorer-Apelbaum, Donna; Weinstock, Marta Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 10 p. 2283 - 2287

15903-94-3 ~% 1476-33-1

文献：Sard, Howard; Kumaran, Govindaraj; Morency, Cynthia; Roth, Bryan L.; Toth, Beth Ann; He, Ping; Shuster, Louis Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 20 p. 4555 - 4559