573764-86-0

• 常用中文名：4-氨基-3-甲基-2-(三氟甲基)苯甲腈
• 常用英文名：4-AMINO-3-METHYL-2-(TRIFLUOROMETHYL)-BENZONITRILE
• CAS号：573764-86-0
• 分子式：C₉H₇F₃N₂
• 分子量：200.161
• 发布时间：2018-11-23 12:11:32
• 更新时间：2024-01-23 16:13:54

名称

• 中文名: 4-氨基-3-甲基-2-(三氟甲基)苯甲腈
• 英文名: 4-Amino-3-methyl-2-(trifluoromethyl)benzonitrile
• 英文别名: 4-amino-3-methyl-1,3-dihydroimidazo[4,5-c]pyridin-2-one; 4-amino-3-methyl-2-trifluoromethylbenzonitrile; 4-Amino-3-methyl-2-(trifluoromethyl)benzonitrile; 4-amino-3-methyl-1,3-dihydro-2H-imidazo<4,5-c>pyridin-2-one; Benzonitrile, 4-amino-3-methyl-2-(trifluoromethyl)-; 2H-Imidazo[4,5-c]pyridin-2-one,4-amino-1,3-dihydro-3-methyl; 4-AMINO-3-METHYL-2-(TRIFLUOROMETHYL)-BENZONITRILE

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 309.5±42.0 °C at 760 mmHg
• 分子式: C₉H₇F₃N₂
• 分子量: 200.161
• 闪点: 141.0±27.9 °C
• 精确质量: 200.056137
• PSA: 49.81000
• LogP: 3.39
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.499
• 储存条件: 2-8°C， 避光干燥

合成路线

573764-81-5 ~87% 573764-86-0

文献：RADIUS HEALTH, INC.; MILLER, Chris, P. Patent: WO2012/47617 A1, 2012 ; Location in patent: Page/Page column 38-39 ; WO 2012/047617 A1

54396-44-0 ~% 573764-86-0

文献：Hamann, Lawrence G.; Manfredi, Mark C.; Sun, Chongqing; Krystek Jr., Stanley R.; Huang, Yanting; Bi, Yingzhi; Augeri, David J.; Wang, Tammy; Zou, Yan; Betebenner, David. A.; Fura, Aberra; Seethala, Ramakrishna; Golla, Rajasree; Kuhns, Joyce E.; Lupisella, John A.; Darienzo, Celia J.; Custer, Laura L.; Price, Jennifer L.; Johnson, James M.; Biller, Scott A.; Zahler, Robert; Ostrowski, Jacek Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 7 p. 1860 - 1864

546434-38-2 ~% 573764-86-0

文献：Hamann, Lawrence G.; Manfredi, Mark C.; Sun, Chongqing; Krystek Jr., Stanley R.; Huang, Yanting; Bi, Yingzhi; Augeri, David J.; Wang, Tammy; Zou, Yan; Betebenner, David. A.; Fura, Aberra; Seethala, Ramakrishna; Golla, Rajasree; Kuhns, Joyce E.; Lupisella, John A.; Darienzo, Celia J.; Custer, Laura L.; Price, Jennifer L.; Johnson, James M.; Biller, Scott A.; Zahler, Robert; Ostrowski, Jacek Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 7 p. 1860 - 1864

13691-92-4 ~% 573764-86-0

文献：RADIUS HEALTH, INC.; MILLER, Chris, P. Patent: WO2012/47617 A1, 2012 ; WO 2012/047617 A1

112641-23-3 ~% 573764-86-0

文献：RADIUS HEALTH, INC.; MILLER, Chris, P. Patent: WO2012/47617 A1, 2012 ; WO 2012/047617 A1

320-51-4 ~% 573764-86-0

文献：RADIUS HEALTH, INC.; MILLER, Chris, P. Patent: WO2012/47617 A1, 2012 ; WO 2012/047617 A1

上下游产品

上游产品  6
573764-81-5 54396-44-0 546434-38-2 13691-92-4
112641-23-3 320-51-4
下游产品  0