25496-72-4

25496-72-4结构式

常用中文名：单油酸甘油酯
常用英文名：Glyceryl monooleate
CAS号：25496-72-4
分子式：C₂₁H₄₀O₄
分子量：356.540
相关类别：研究领域其他
发布时间：2018-07-12 18:32:55
更新时间：2024-01-02 10:57:00
单酸甘油酯是一种无毒、可生物降解、生物相容的亲脂性甘油脂肪酸酯。甘油单油酸酯具有溶血特性。甘油单油酸酯与胆盐一起用作乳化剂和吸收促进剂。单酸甘油酯可用于药物传递系统和体外siRNA传递[1][2]。

中文名	甘油单油酸酯
英文名	Glycerol mono-oleate
中文别名	单油酸甘油酯
英文别名	Glyceryl cis-9-octadecenoate 9-Octadecenoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, (9Z)- Oleic monoglyceride 9-Octadecenoic acid (9Z)-, monoester with 1,2,3-propanetriol 1-monooleoyl-rac-glycerol 1-(cis-9-Octadecenoyl)-rac-glycerol 1-Monooleoylglycerol rac-Glycerol 1-monooleate Glycerin 1-monooleate glycerol monooleate rac 1-Oleoyl Glycerol 4,5-Dihydroxypentyl (7Z)-7-hexadecenoate Glycerin monooleate Oleic acid glycerol monoester 1,3-Dihydroxypropan-2-yl (9Z)-octadec-9-enoate Glycerine monooleate 1-O-Oleyl-rac-glycerol 1-oleoyl glycerol 1-OLEOYLGLYCEROL OLEOYL GLYCEROL GLYCEROL OLEATE 9-Octadecenoic acid, 2,3-dihydroxypropyl ester, (9Z)- 1,3-Dihydroxy-2-propanyl (9Z)-9-octadecenoate MFCD00042735 2,3-Dihydroxypropyl (9Z)-9-octadecenoate 2,3-Dihydroxypropyl oleate GLYCEROL MONO-OLEATE MONO OLEIN Glycerine oleate 1-GLYCERYL OLEATE Glycerol Alpha-Monooleate GLYCERYL MONOOLEATE 2,3-Dihydroxypropyl (9Z)-octadec-9-enoate a-Monoolein DL-ALPHA-MONOOLEIN Monoolein 9 C18:1 Danisco MO 90 GLYCEROL MONO OLEATE Monoolein (VAN) 2-hydroxy-1-(hydroxymethyl)ethyl (9Z)-octadec-9-enoate 1-Oleoyl-rac-glycerol 2-Oleoylglycerol Glyceryl Monooleate (VAN) RAC.-1-OLEOYL-GLYCEROL BIOCHEMICA (9Z)-9-Octadecenoic Acid 2,3-Dihydroxypropyl Ester dl-α-Monoolein Glycerol α-monooleate UNII:D3AEF6S35P α-Monoolein rac-1-Monooleoylglycerol 7-Hexadecenoic acid, 4,5-dihydroxypentyl ester, (7Z)- 9-Octadecenoic acid (9Z)-, ester with 1,2,3-propanetriol Monoolein 1-Mono(cis-9-octacenoyl)glycerol EINECS 247-038-6 Aldo HMO

描述	单酸甘油酯是一种无毒、可生物降解、生物相容的亲脂性甘油脂肪酸酯。甘油单油酸酯具有溶血特性。甘油单油酸酯与胆盐一起用作乳化剂和吸收促进剂。单酸甘油酯可用于药物传递系统和体外siRNA传递[1][2]。
相关类别	研究领域 >> 其他信号通路 >> 其他 >> 其他
参考文献	[1]. Milak S, et al. Glycerol monooleate liquid crystalline phases used in drug delivery systems. Int J Pharm. 2015 Jan 30;478(2):569-87. [2]. Zhen G, et al. Glycerol monooleate-based nanocarriers for siRNA delivery in vitro. Mol Pharm. 2012 Sep 4;9(9):2450-7.

密度	1.0±0.1 g/cm3
沸点	483.3±35.0 °C at 760 mmHg
熔点	36 - 40ºC
分子式	C₂₁H₄₀O₄
分子量	356.540
闪点	155.4±19.4 °C
精确质量	356.292664
PSA	66.76000
LogP	6.71
外观性状	白色蜡质糊
蒸汽压	0.0±2.8 mmHg at 25°C
折射率	1.479
储存条件	−20°C
水溶解性	chloroform: 50 mg/mL, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RK1300000

CHEMICAL NAME :: Olein, mono-

CAS REGISTRY NUMBER :: 25496-72-4

LAST UPDATED :: 199701

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C21-H40-O4

MOLECULAR WEIGHT :: 356.61

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 5(5),391,1986 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83110 No. of Facilities: 4016 (estimated) No. of Industries: 41 No. of Occupations: 51 No. of Employees: 74220 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83110 No. of Facilities: 9941 (estimated) No. of Industries: 81 No. of Occupations: 78 No. of Employees: 159120 (estimated) No. of Female Employees: 39063 (estimated)

危险品运输编码	NONH for all modes of transport
WGK德国	1

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