59417-86-6

• 常用中文名：6-FLUOROBENZO(a)PYRENE
• 常用英文名：6-FLUOROBENZO(a)PYRENE
• CAS号：59417-86-6
• 分子式：C₂₀H₁₁F
• 分子量：270.30000
• 发布时间：2017-01-15 03:54:40
• 更新时间：2025-09-23 15:32:41

名称

• 英文名: 6-fluorobenzo[a]pyrene
• 英文别名: 6-Fluorobenzo(a)pyrene; Benzo(a)pyrene,6-fluoro

物化性质

• 密度: 1.349g/cm3
• 沸点: 470.4ºC at 760 mmHg
• 分子式: C₂₀H₁₁F
• 分子量: 270.30000
• 闪点: 203.5ºC
• 精确质量: 270.08400
• LogP: 5.87630
• 折射率: 1.86

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DJ6380270 CHEMICAL NAME : Benzo(a)pyrene, 6-fluoro- CAS REGISTRY NUMBER : 59417-86-6 LAST UPDATED : 199706 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C20-H11-F MOLECULAR WEIGHT : 270.31 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 35 mg/kg/1W-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 49 mg/kg/60W-I TOXIC EFFECTS : Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 9 mg/kg TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Tumorigenic - tumors at site of application REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983 TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 16 mg/kg/60W-I TOXIC EFFECTS : Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors REFERENCE : JJIND8 JNCI, Journal of the National Cancer Institute. (Washington, DC) V.61-79, 1978-87. For publisher information, see JNCIEQ. Volume(issue)/page/year: 71,309,1983

合成路线

50-32-8 ~21% 59417-86-6

文献：Laali, Kenneth K.; Tanaka, Mutsuo; Forohar, Farhad; Cheng, Michael; Fetzer, John C. Journal of Fluorine Chemistry, 1998 , vol. 91, # 2 p. 185 - 190

21248-00-0 ~% 59417-86-6

文献：Cremonesi, Paolo; Cavalieri, Ercole L.; Rogan, Eleanor G. Journal of Organic Chemistry, 1989 , vol. 54, # 15 p. 3561 - 3570

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