14149-31-6

• 常用中文名：4-苯基哌啶-2,6-二酮
• 常用英文名：2,6-Piperidinedione,4-phenyl-
• CAS号：14149-31-6
• 分子式：C₁₁H₁₁NO₂
• 分子量：189.21100
• 发布时间：2016-06-23 17:01:25
• 更新时间：2025-08-25 09:26:28

名称

• 中文名: 4-苯基哌啶-2,6-二酮
• 英文名: 4-phenylpiperidine-2,6-dione
• 英文别名: 3-Phenylglutarimide; Glutarimide,3-phenyl; 4-Phenyl-2,6-piperidinedione; 4-phenyl-piperidine-2,6-dione; 4-phenylglutarimide; 4-Phenyl-piperidin-2,6-dion; 4-phenyl-piperidin-2,6-dione

物化性质

• 密度: 1.185g/cm3
• 沸点: 392.3ºC at 760mmHg
• 熔点: 173-174℃
• 分子式: C₁₁H₁₁NO₂
• 分子量: 189.21100
• 闪点: 176.6ºC
• 精确质量: 189.07900
• PSA: 46.17000
• LogP: 1.53560
• 蒸汽压: 2.31E-06mmHg at 25°C
• 折射率: 1.553
• 储存条件: 2-8℃

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : MA5350000 CHEMICAL NAME : Glutarimide, 3-phenyl- CAS REGISTRY NUMBER : 14149-31-6 BEILSTEIN REFERENCE NO. : 0146423 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H11-N-O2 MOLECULAR WEIGHT : 189.23 WISWESSER LINE NOTATION : T6VMVTJ ER HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 80 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 10,243,1960 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 173,115,1968

安全

• 海关编码: 2925190090

合成路线

2628-87-7 57-13-6 ~79% 14149-31-6

文献：Klinge Pharma GmbH Patent: EP1042315 B1, 2004 ; Location in patent: Page 59 ;

4165-96-2 57-13-6 ~72% 14149-31-6

文献：Romeo, Giuseppe; Materia, Luisa; Modica, Maria N.; Pittal, Valeria; Salerno, Loredana; Siracusa, Maria A.; Manetti, Fabrizio; Botta, Maurizio; Minneman, Kenneth P. European Journal of Medicinal Chemistry, 2011 , vol. 46, # 7 p. 2676 - 2690

4165-96-2 ~98% 14149-31-6

文献：Rani; Cui; Ubukata; Osada Journal of Antibiotics, 1995 , vol. 48, # 10 p. 1179 - 1181

19006-47-4 ~61% 14149-31-6

文献：Kinoshita, Takamasa; Okamoto, Kazuko; Clardy, Jon Synthesis, 1985 , # 4 p. 402 - 403

6456-86-6 ~% 14149-31-6

文献：Burger; Hofstetter Journal of Organic Chemistry, 1959 , vol. 24, p. 1290,1292

4160-80-9 ~% 14149-31-6

文献：Mallard; Wilson Journal of the American Pharmaceutical Association (1912-1977), 1957 , vol. 46, p. 176

上下游产品

上游产品  6
2628-87-7 57-13-6 4165-96-2 19006-47-4
6456-86-6 4160-80-9
下游产品  2
771-99-3 6973-55-3

海关

海关编码	2925190090
中文概述	2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%