67730-11-4

• 常用中文名：2-氨基-6-甲基二吡啶[1,2-A:3’,2’-D]咪唑盐酸盐水合
• 常用英文名：2-AMINO-6-METHYLDIPYRIDO[1,2-A:3',2'-D]IMIDAZOLE, HYDROCHLORIDE MONOHYDRATE
• CAS号：67730-11-4
• 分子式：C₁₁H₁₃ClN₄O
• 分子量：252.70000
• 发布时间：2018-12-30 13:16:18
• 更新时间：2024-01-04 16:21:59

名称

• 中文名: 2-氨基-6-甲基二吡啶[1,2-A:3’,2’-D]咪唑盐酸盐水合
• 英文名: Glu-P-1
• 中文别名: 2-氨基-6-甲基二吡啶并(1,2-A:3',2'-D)咪唑盐酸盐
• 英文别名: 6-Me-Glu-P-2; 2-amino-6-methyldipyridi<1,2-a:3',2'-d>imidazole

物化性质

• 密度: 1.41g/cm3
• 沸点: 363.7ºC at 760mmHg
• 熔点: >300ºC
• 分子式: C₁₁H₁₃ClN₄O
• 分子量: 252.70000
• 闪点: 173.8ºC
• 精确质量: 252.07800
• PSA: 65.44000
• LogP: 3.09200
• 储存条件: 库房通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : JM5620000 CAS REGISTRY NUMBER : 67730-11-4 LAST UPDATED : 199612 DATA ITEMS CITED : 23 MOLECULAR FORMULA : C11-H10-N4 MOLECULAR WEIGHT : 198.25 WISWESSER LINE NOTATION : T B656 AN CN HNJ DZ J1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 9100 mg/kg/68W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 15200 mg/kg/58W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 17512 mg/kg/57W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors TYPE OF TEST : TD - Toxic dose (other than lowest) ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 17212 mg/kg/47W-C TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Vascular - tumors Liver - tumors TYPE OF TEST : Morphological transformation TYPE OF TEST : Specific locus test TYPE OF TEST : DNA damage MUTATION DATA TYPE OF TEST : DNA damage TEST SYSTEM : Mammal - species unspecified Lymphocyte DOSE/DURATION : 10 umol/L REFERENCE : BBRCA9 Biochemical and Biophysical Research Communications. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 96,611,1980 *** REVIEWS *** IARC Cancer Review:Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,223,1986 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 40,223,1986 IARC Cancer Review:Group 2B IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

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