10017-44-4

• 常用中文名：左旋肉碱盐酸盐
• 常用英文名：D-(+)-Carnitine hydrochloride
• CAS号：10017-44-4
• 分子式：C₇H₁₆ClNO₃
• 分子量：197.660
• 相关类别： 信号通路 其他 其他
• 发布时间：2018-04-18 08:00:00
• 更新时间：2024-01-02 11:11:55
• L-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) 已被用于研究麦角硫因素转运蛋白 SLC22A4 和肉毒碱转运蛋白 SLC22A5。L-Carnitine hydrochloride还被用于使棕榈酸进入线粒体。

名称

• 中文名: L-肉碱盐酸盐
• 英文名: L-Carnitine hydrochloride
• 中文别名: 左旋肉碱盐酸盐
• 英文别名: 3-carboxy-2-hydroxy-n,n,n-trimethyl-,chloride,(s)-1-propanaminiu; (2R)-3-carboxy-2-hydroxy-N,N,N-trimethylpropan-2-aminium chloride; CARNITINE HYDROCHLORIDE, (+)-; d-Carnitine chloride; (+)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride; Vitamine BT; 1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride, (2S)- (1:1); D-Carnitine hydrochloride; [3H]-L-(-)-Carnitine hydrochloride; (2S)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride; S-Cartininehydrochloride; 1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,chloride,(2S); (S)-Carnitine hydrochloride; (+)-CARNITINE HYDROCHLORIDE; 1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,chloride,(S); (2S)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride; R-(-)-carnitine hydrochloride; 1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,chloride,(2S)-(9CI)

物化性质

• 分子式: C₇H₁₆ClNO₃
• 分子量: 197.660
• 精确质量: 197.081863
• PSA: 57.53000

生物活性

• 描述: L-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) 已被用于研究麦角硫因素转运蛋白 SLC22A4 和肉毒碱转运蛋白 SLC22A5。L-Carnitine hydrochloride还被用于使棕榈酸进入线粒体。
• 相关类别:
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Horvath GA, et al. Newborn screening for MCAD deficiency: experience of the first three years in British Columbia, Canada. Can J Public Health. 2008 Jul-Aug;99(4):276-80.

  [2]. Leenders JJ, et al. Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity. J Biol Chem. 2010 Aug 27;285(35):27449-56.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : BP2979120 CHEMICAL NAME : Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, chloride, (+)- CAS REGISTRY NUMBER : 10017-44-4 LAST UPDATED : 198912 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C7-H15-N-O3.Cl HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5700 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Lungs, Thorax, or Respiration - cyanosis REFERENCE : ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 3,28,1959

安全

• 海关编码: 2923900090

海关

海关编码	2923900090
中文概述	2923900090 其他季铵盐及季铵碱。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%