981-01-1

• 常用中文名：[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate
• 常用英文名：[(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate
• CAS号：981-01-1
• 分子式：C₂₁H₂₃NO₅
• 分子量：369.41100
• 相关类别： 生物化工 氨基酸及其衍生物 谷氨酰胺类衍生物
• 发布时间：2016-07-25 20:52:01
• 更新时间：2024-04-05 14:19:57

名称

• 英文名: [(4R,4aS,7aR,12bS)-9-methoxy-3-methyl-7-oxo-2,4,7a,13-tetrahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a-yl] propanoate
• 英文别名: 14-Propionyloxy-kodeinon; 14-Propionyloxycodeinon; Codeinone,14-hydroxy-,propionate; Morphinan-6-one,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-14-(1-oxopropoxy)-,(5alpha); Morphinan-6-one,7,8-didehydro-4,5-epoxy-3-methoxy-17-methyl-14-(1-oxopropoxy)-,(5)

物化性质

• 密度: 1.35g/cm3
• 沸点: 514.5ºC at 760 mmHg
• 分子式: C₂₁H₂₃NO₅
• 分子量: 369.41100
• 闪点: 265ºC
• 精确质量: 369.15800
• PSA: 65.07000
• LogP: 1.72300
• 折射率: 1.631

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QD2167000 CHEMICAL NAME : Morphinan-6-one, 7,8-didehydro-4,5-alpha-epoxy-14-hydroxy-3-methoxy-17 -methyl-, propionate (ester) CAS REGISTRY NUMBER : 981-01-1 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C21-H23-N-O5 MOLECULAR WEIGHT : 369.45 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 110 mg/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 16(Suppl),68T,1964

合成路线

4829-46-3 ~% 981-01-1

文献：Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

103458-67-9 ~% 981-01-1

文献：Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

100740-63-4 ~% 981-01-1

文献：Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

508-54-3 123-62-6 ~% 981-01-1

文献：Currie,A.C. et al. Journal of the Chemical Society, 1960 , p. 773 - 781

上下游产品

上游产品  5
4829-46-3 103458-67-9 100740-63-4 508-54-3
123-62-6
下游产品  0