104485-01-0

• 常用中文名：[(2R)-2-pyrrolidin-1-ylcyclohexyl] N-(3-pentoxyphenyl)carbamate
• 常用英文名：[(2R)-2-pyrrolidin-1-ylcyclohexyl] N-(3-pentoxyphenyl)carbamate
• CAS号：104485-01-0
• 分子式：C₂₂H₃₄N₂O₃
• 分子量：374.51700
• 发布时间：2017-06-15 12:16:26
• 更新时间：2025-08-27 11:06:52

名称

• 英文名: (2R)-2-(1-Pyrrolidinyl)cyclohexyl [3-(pentyloxy)phenyl]carbamate

物化性质

• 密度: 1.1g/cm3
• 沸点: 463.8ºC at 760mmHg
• 分子式: C₂₂H₃₄N₂O₃
• 分子量: 374.51700
• 闪点: 234.3ºC
• 精确质量: 374.25700
• PSA: 54.29000
• LogP: 5.16260
• 蒸汽压: 8.82E-09mmHg at 25°C
• 折射率: 1.551

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : FD0406500 CHEMICAL NAME : Carbamic acid, (3-(pentyloxy)phenyl)-, 2-(1-pyrrolidinyl)cyclohexyl ester, trans-(+-)- CAS REGISTRY NUMBER : 104485-01-0 LAST UPDATED : 199503 DATA ITEMS CITED : 12 MOLECULAR FORMULA : C22-H34-N2-O3 MOLECULAR WEIGHT : 374.58 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1030 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 70 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 283 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 11800 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 790 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 56 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 122 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10300 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : >60 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 2950 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 58 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 105 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAOBAS Farmaceuticky Obzor. Pharmaceutical Review. (PNS - Ustredna Expedicia a Dovoz Tlace, Gottwaldovo nam. 6, 813 81 Bratislava, Czechoslovakia) V.30- 1961- Volume(issue)/page/year: 45,355,1976