CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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YS4983000
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CHEMICAL NAME :
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Urea, 1-(2-chloroethyl)-3-(cis-4-hydroxycyclohexyl)-1-nitro so-
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CAS REGISTRY NUMBER :
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52049-26-0
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LAST UPDATED :
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199007
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DATA ITEMS CITED :
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3
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MOLECULAR FORMULA :
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C9-H16-Cl-N3-O3
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MOLECULAR WEIGHT :
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249.73
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WISWESSER LINE NOTATION :
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L6TJ AQ DMVNNO&2G -CIS
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intraperitoneal
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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60180 ug/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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NCISP* National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. (Bethesda, MD 20205) Volume(issue)/page/year: JAN1986
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TYPE OF TEST :
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LD10 - Lethal Dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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25 mg/kg
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TOXIC EFFECTS :
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Tumorigenic - active as anti-cancer agent
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REFERENCE :
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ANBCB3 Antibiotics and Chemotherapy (Basel). (S. Karger AG, Postfach CH-4009 Basel, Switzerland) V.17- 1971- Volume(issue)/page/year: 23,64,1978
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TYPE OF TEST :
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LDLo - Lowest published lethal dose
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ROUTE OF EXPOSURE :
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Intrapleural
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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33 mg/kg
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TOXIC EFFECTS :
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Details of toxic effects not reported other than lethal dose value
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REFERENCE :
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JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,634,1975
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