25514-11-8

• 常用中文名：2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-
• 常用英文名：2(1H)-Quinazolinone,6-chloro-3-ethyl-3,4-dihydro-4-hydroxy-4-phenyl-
• CAS号：25514-11-8
• 分子式：C₁₆H₁₅ClN₂O₂
• 分子量：302.75600
• 发布时间：2016-05-22 03:59:22
• 更新时间：2025-09-21 20:07:35

名称

• 英文名: 6-chloro-3-ethyl-4-hydroxy-4-phenyl-1H-quinazolin-2-one
• 英文别名: 6-chloro-3-ethyl-4-hydroxy-4-phenyl-3,4-dihydro-1H-quinazolin-2-one

物化性质

• 密度: 1.322g/cm3
• 沸点: 537.6ºC at 760mmHg
• 分子式: C₁₆H₁₅ClN₂O₂
• 分子量: 302.75600
• 闪点: 279ºC
• 精确质量: 302.08200
• PSA: 52.57000
• LogP: 3.47670
• 蒸汽压: 2.17E-12mmHg at 25°C
• 折射率: 1.625

合成路线

80189-40-8 ~89% 25514-11-8

文献：Yamamoto Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 8 p. 2135 - 2156

719-59-5 109-90-0 ~84% 25514-11-8

文献：E. I. Du Pont de Nemours and Company Patent: US4258187 A1, 1981 ;

26381-66-8 ~% 25514-11-8

文献：Yamamoto Chemical and Pharmaceutical Bulletin, 1981 , vol. 29, # 8 p. 2135 - 2156

719-59-5 75-04-7 530-62-1 ~% 25514-11-8

文献：Barrow, James C.; Rittle, Kenneth E.; Reger, Thomas S.; Yang, Zhi-Qiang; Bondiskey, Phung; McGaughey, Georgia B.; Bock, Mark G.; Hartman, George D.; Tang, Cuyue; Ballard, Jeanine; Kuo, Yuhsin; Prueksaritanont, Thomayant; Nuss, Cindy E.; Doran, Scott M.; Fox, Steven V.; Garson, Susan L.; Kraus, Richard L.; Li, Yuxing; Marino, Michael J.; Kuzmick Graufelds, Valerie; Uebele, Victor N.; Renger, John J. ACS Medicinal Chemistry Letters, 2010 , vol. 1, # 2 p. 75 - 79

120698-08-0 ~% 25514-11-8

文献：Schleuder, M.; Richter, P.; Brandner, Anke; Morgenstern O. Pharmazie, 1989 , vol. 44, # 4 p. 259 - 260

120195-14-4 ~% 25514-11-8

文献：Schleuder, M.; Richter, P.; Brandner, Anke; Morgenstern O. Pharmazie, 1989 , vol. 44, # 4 p. 259 - 260

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80189-40-8 719-59-5 109-90-0 26381-66-8
75-04-7 530-62-1 120698-08-0 120195-14-4
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