59795-94-7

• 常用中文名：Neoaureothin
• 常用英文名：Neoaureothin
• CAS号：59795-94-7
• 分子式：C₂₈H₃₁NO₆
• 分子量：477.54900
• 发布时间：2016-09-26 17:30:41
• 更新时间：2025-09-11 20:48:33
• Neoaureothin is a bacterial metabolite and androgen receptor (AR) antagonist that inhibits binding of dihydrotestosterone (DHT) to ARs and inhibits DHT-induced expression of prostate-specific antigen in LNCaP cells. It also has nematocidal activity against the pine wood nematode B. xylophilus and increases survival of P. densiflora trees inoculated with B. xylophilus.

名称

• 英文名: 2-methoxy-3,5-dimethyl-6-[(4Z)-4-[(2E,4E,6E)-2,4,6-trimethyl-7-(4-nitrophenyl)hepta-2,4,6-trienylidene]oxolan-2-yl]pyran-4-one

物化性质

• 密度: 1.2g/cm3
• 沸点: 660.7ºC at 760 mmHg
• 分子式: C₂₈H₃₁NO₆
• 分子量: 477.54900
• 闪点: 241ºC
• 精确质量: 477.21500
• PSA: 94.49000
• LogP: 7.08050
• 折射率: 1.588

合成路线

856859-87-5 544-97-8 ~88% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

856859-84-2 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

846031-12-7 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

59488-84-5 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

846031-10-5 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

846031-08-1 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

846031-09-2 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

96552-61-3 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

159213-40-8 ~% 59795-94-7

文献：Jacobsen, Mikkel F.; Moses, John E.; Adlington, Robert M.; Baldwin, Jack E. Tetrahedron, 2006 , vol. 62, # 8 p. 1675 - 1689

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856859-87-5 544-97-8 856859-84-2 846031-12-7
59488-84-5 846031-10-5 846031-08-1 846031-09-2
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