57436-65-4

• 常用中文名：4-Thiomorpholinamine,N-[[2-(1-methyl-5-nitro-1H-imidazol-2-yl)-4-thiazolyl]methylene]-,1,1-dioxide
• 常用英文名：4-Thiomorpholinamine,N-[[2-(1-methyl-5-nitro-1H-imidazol-2-yl)-4-thiazolyl]methylene]-,1,1-dioxide
• CAS号：57436-65-4
• 分子式：C₁₂H₁₄N₆O₄S₂
• 分子量：370.40700
• 发布时间：2017-11-16 12:11:13
• 更新时间：2024-04-03 20:24:54

名称

• 英文名: (E)-N-(1,1-dioxo-1,4-thiazinan-4-yl)-1-[2-(1-methyl-5-nitroimidazol-2-yl)-1,3-thiazol-4-yl]methanimine
• 英文别名: 4-Thiomorpholinamine,N-((2-(1-methyl-5-nitro-1H-imidazol-2-yl)-4-thiazolyl)methylene)-,1,1-dioxide; 2-(1-methyl-5-nitroimidazol-2-yl)-4-(thiomorpholinoiminomethyl)thiazole-1',1'-dioxide

物化性质

• 密度: 1.72g/cm3
• 沸点: 753ºC at 760mmHg
• 分子式: C₁₂H₁₄N₆O₄S₂
• 分子量: 370.40700
• 闪点: 409.2ºC
• 精确质量: 370.05200
• PSA: 162.89000
• LogP: 2.05800
• 折射率: 1.779

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XM0100000 CHEMICAL NAME : 4-Thiomorpholinamine, N-((2-(1-methyl-5-nitro-1H-imidazol-2-yl)-4-thiazolyl )methylene)-, 1,1-dioxide CAS REGISTRY NUMBER : 57436-65-4 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C12-H14-N6-O4-S2 MOLECULAR WEIGHT : 370.44 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >1600 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,946,1977 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 20,946,1977

合成路线

57436-49-4 ~% 57436-65-4

文献：Neville; Verge Journal of Medicinal Chemistry, 1977 , vol. 20, # 7 p. 946 - 949

62720-06-3 ~% 57436-65-4

文献：Neville; Verge Journal of Medicinal Chemistry, 1977 , vol. 20, # 7 p. 946 - 949

57436-62-1 26494-76-8 ~% 57436-65-4

文献：Neville; Verge Journal of Medicinal Chemistry, 1977 , vol. 20, # 7 p. 946 - 949

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