693-33-4

• 常用中文名：十六烷基甜菜碱
• 常用英文名：Hexadecylbetaine
• CAS号：693-33-4
• 分子式：C₂₁H₄₅NO₃
• 分子量：359.58700
• 发布时间：2019-02-21 00:07:38
• 更新时间：2024-01-03 00:19:54

名称

• 中文名: 氢氧化(羧甲基二甲基十六烷基铵)内盐
• 英文名: 2-[hexadecyl(dimethyl)azaniumyl]acetate
• 中文别名: 十六烷基甜菜碱
• 英文别名: cetyl betaine; Lonzaine 16S; N-hexadecyl-betaine; C16BET; N,N-Dimethyl-N-hexadecylglycine; Palmityldimethylbetaine; N-n-hexadecyl-N,N-dimethyl-glycin; Carboxymethyl-hexadecyl-dimethyl-ammonium-betain; carboxymethyl-hexadecyl-dimethyl-ammonium betaine; Hexadecylbetaine; EINECS 211-748-4

物化性质

• 密度: 0.9732
• 沸点: 465.41°C
• 分子式: C₂₁H₄₅NO₃
• 分子量: 359.58700
• 精确质量: 359.34000
• PSA: 49.36000
• LogP: 5.54030
• 折射率: 1.5614
• 储存条件: 库房低温通风干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : ML9110000 CHEMICAL NAME : 1-Hexadecanaminium, N-(carboxymethyl)-N,N-dimethyl-, hydroxide, inner salt CAS REGISTRY NUMBER : 693-33-4 BEILSTEIN REFERENCE NO. : 3676787 LAST UPDATED : 199710 DATA ITEMS CITED : 6 MOLECULAR FORMULA : C20-H41-N-O2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1620 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 16,41,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rat DOSE/DURATION : >16 gm/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - effect, not otherwise specified Skin and Appendages - dermatitis, other (after systemic exposure) Skin and Appendages - hair REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 16,41,1991 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 150 mg/kg TOXIC EFFECTS : Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea REFERENCE : FAATDF Fundamental and Applied Toxicology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1981- Volume(issue)/page/year: 16,41,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M2947 No. of Facilities: 15 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 162 (estimated)

合成路线

112-69-6 3926-62-3 ~% 693-33-4

文献：Tanaka; Kato Yakugaku Zasshi, 1943 , vol. 63, p. 593 Chem.Abstr., 1951 , p. 5100

5466-51-3 ~% 693-33-4

文献：Swain et al. Journal of Organic Chemistry, 1953 , vol. 18, p. 1087,1088

112-82-3 ~% 693-33-4

文献：Beckett,A.H.; Woodward,R.J. Journal of Pharmacy and Pharmacology, 1963 , vol. 15, p. 422 - 431

74729-09-2 ~% 67-56-1 693-33-4

文献：Al-Lohedan, Hamad; Bunton, Clifford A.; Romsted, Laurence S. Journal of Physical Chemistry, 1981 , vol. 85, # 13 p. 2123 - 2129