7548-46-1

• 常用中文名：(8S,9S,13S,14S)-17-(2-bromoethynyl)-3,17-dimethoxy-13-methyl-7,8,9,11, 12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene
• 常用英文名：(8S,9S,13S,14S)-17-(2-bromoethynyl)-3,17-dimethoxy-13-methyl-7,8,9,11, 12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene
• CAS号：7548-46-1
• 分子式：C₂₂H₂₇BrO₂
• 分子量：403.35300
• 发布时间：2016-01-23 10:57:54
• 更新时间：2024-02-11 13:46:45

名称

• 英文名: (8S,9S,13S,14S)-17-(2-bromoethynyl)-3,17-dimethoxy-13-methyl-7,8,9,11, 12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene
• 英文别名: bdh-6140

物化性质

• 密度: 1.31g/cm3
• 沸点: 481.5ºC at 760 mmHg
• 分子式: C₂₂H₂₇BrO₂
• 分子量: 403.35300
• 闪点: 201ºC
• 精确质量: 402.11900
• PSA: 18.46000
• LogP: 5.29230
• 折射率: 1.594
• 储存条件: 通风低温干燥

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : RC8924700 CHEMICAL NAME : 19-Nor-17-alpha-pregna-1,3,5(10)-trien-20-yne, 21-bromo-3,17-dimethoxy- CAS REGISTRY NUMBER : 7548-46-1 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C22-H27-Br-O2 MOLECULAR WEIGHT : 403.40 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 1500 ug/kg SEX/DURATION : female 1-5 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 53,443,1966 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 24 ug/kg SEX/DURATION : female 3 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 53,443,1966 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 180 ug/kg SEX/DURATION : female 1-5 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated) REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 53,443,1966 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 36300 ng/kg SEX/DURATION : female 3 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - uterus, cervix, vagina REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 53,443,1966

合成路线

7548-45-0 ~% 7548-46-1

文献：Burgess; Cooley; Feather; Petrow Tetrahedron, 1967 , vol. 23, # 10 p. 4111 - 4116