108138-27-8

• 常用中文名：1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• 常用英文名：1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• CAS号：108138-27-8
• 分子式：C₂₀H₁₆F₃N₃O₃
• 分子量：403.35500
• 发布时间：2017-01-01 06:46:52
• 更新时间：2025-09-18 12:06:12

名称

• 英文名: 1-(2,4-difluorophenyl)-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
• 英文别名: t 1814

物化性质

• 密度: 1.48g/cm3
• 沸点: 611ºC at 760 mmHg
• 分子式: C₂₀H₁₆F₃N₃O₃
• 分子量: 403.35500
• 闪点: 323.3ºC
• 精确质量: 403.11400
• PSA: 74.57000
• LogP: 2.90960
• 蒸汽压: 8.74E-16mmHg at 25°C
• 折射率: 1.62

合成路线

110-85-0 103995-01-3 ~46% 108138-27-8

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

367-25-9 ~% 108138-27-8

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

446-17-3 ~% 108138-27-8

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

98349-24-7 ~% 108138-27-8

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

108138-17-6 ~% 108138-27-8

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

108115-67-9 ~% 108138-27-8

文献：Renau, Thomas E.; Sanchez, Joseph P.; Shapiro, Martin A.; Dever, Julie A.; Gracheck, Stephen J.; Domagala, John M. Journal of Medicinal Chemistry, 1995 , vol. 38, # 15 p. 2974 - 2977

上下游产品

上游产品  7
110-85-0 103995-01-3 367-25-9 446-17-3
98349-24-7 108138-17-6 108115-67-9
下游产品  0