848357-31-3

• 常用中文名：1-乙酰基-1H-噻吩并[3,2-c]吡唑-5-羧酸甲酯
• 常用英文名：methyl 1-acetylthieno[3,2-c]pyrazole-5-carboxylate
• CAS号：848357-31-3
• 分子式：C₉H₈N₂O₃S
• 分子量：224.236
• 发布时间：2018-11-23 17:53:17
• 更新时间：2025-08-27 15:58:35

名称

• 中文名: 1-乙酰基-1H-噻吩并[3,2-c]吡唑-5-羧酸甲酯
• 英文名: methyl 1-acetylthieno[3,2-c]pyrazole-5-carboxylate
• 英文别名: Methyl O-Methyl-18-epi-reserpate; Mepiserpate; 2,3,11-trimethoxy-1,2,3,4,4a,5,7,8,13,13b,14,14a-dodecahydroisoquinolino[3,2-a]; Methyl 1-acetyl-1H-thieno[3,2-c]pyrazole-5-carboxylate; Methyl 18-epi-O-methyl-3-isoreserpate; Methyl O-Methyl-18-epireserp; Methyl-18-epi-O-methyl-reserpat; O-Methyl-18-epireserpic Acid Methyl Ester; 18-epi-O-Methylreserpic Acid Methyl Ester; 1-acetyl-1H-thieno[3,2-c]pyrazole-5-carboxylic acid methyl ester; 1H-Thieno[3,2-c]pyrazole-5-carboxylic acid, 1-acetyl-, methyl ester; 11,17,18-trimethoxy-yohimbane-16-carboxylic acid methyl ester; b-carboline-1-carboxylic acid methyl ester

物化性质

• 密度: 1.5±0.1 g/cm3
• 沸点: 382.7±45.0 °C at 760 mmHg
• 分子式: C₉H₈N₂O₃S
• 分子量: 224.236
• 闪点: 185.3±28.7 °C
• 精确质量: 224.025558
• PSA: 89.43000
• LogP: 2.26
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.678

合成路线

501082-56-0 108-24-7 ~50% 848357-31-3

文献：AVENTIS PHARMACEUTICALS INC. Patent: WO2005/26175 A1, 2005 ; Location in patent: Page/Page column 75-76 ; WO 2005/026175 A1

501082-56-0 127-08-2 ~54% 848357-31-3

文献：BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH and CO KG Patent: WO2007/76228 A2, 2007 ; Location in patent: Page/Page column 24 ; WO 2007/076228 A2

501082-56-0 542-56-3 ~% 848357-31-3

文献：SU, Wei-Guo; JIA, Hong; DAI, Guangxiu Patent: US2012/245178 A1, 2012 ; Location in patent: Page/Page column 16 ; US 20120245178 A1

19432-69-0 ~% 848357-31-3

文献：HUTCHISON MEDIPHARMA LIMITED; SU, Wei-Guo; JIA, Hong; DAI, Guangxiu Patent: WO2011/79804 A1, 2011 ; WO 2011/079804 A1

1918-79-2 ~% 848357-31-3

文献：HUTCHISON MEDIPHARMA LIMITED; SU, Wei-Guo; JIA, Hong; DAI, Guangxiu Patent: WO2011/79804 A1, 2011 ; WO 2011/079804 A1

56921-01-8 ~% 848357-31-3

文献：HUTCHISON MEDIPHARMA LIMITED; SU, Wei-Guo; JIA, Hong; DAI, Guangxiu Patent: WO2011/79804 A1, 2011 ; WO 2011/079804 A1

上下游产品

上游产品  7
501082-56-0 108-24-7 127-08-2 542-56-3
19432-69-0 1918-79-2 56921-01-8
下游产品  1
848358-06-5