3543-72-4

• 常用中文名：1-甲基-5-硝基-1H-苯并咪唑-2-丁酸乙酯
• 常用英文名：1-Methyl-5-nitro-1H-benzimidazole-2-butanoic Acid Ethyl Ester
• CAS号：3543-72-4
• 分子式：C₁₄H₁₇N₃O₄
• 分子量：291.302
• 发布时间：2018-06-12 18:04:12
• 更新时间：2026-07-02 23:07:12

名称

• 中文名: 1-甲基-5-硝基-1H-苯并咪唑-2-丁酸乙酯
• 英文名: ethyl 4-(1-methyl-5-nitrobenzimidazol-2-yl)butanoate
• 中文别名: 2-甲基-5-硝基-1H-苯并咪唑-2-丁酸乙酯; 苯达莫司汀相关杂质18; 1-甲基-5-硝基-1H-苯并咪唑-2-丁酸乙酯 苯达莫司汀中间体; 盐酸苯达莫司汀/1-甲基-5-硝基-1H-苯并咪唑-2-丁酸乙酯; 苯达莫司汀杂质21; 盐酸苯达莫司汀的原料; 5-硝基-1-甲基-1H-苯并咪唑-2-丁酸丁酯; 盐酸苯达莫斯汀中间体-2; 苯达莫司汀硝基酸乙酯杂质; 苯达莫斯汀杂质8; 2-甲基-5-硝基-1H-苯并咪唑-2-丁酸乙酯(盐酸苯达莫司汀中间体); 1-甲基-5-硝基-1H-苯并咪唑-2-丁酸乙酯(盐酸苯达莫司汀中间体); 苯达莫司汀硝基乙酯杂质; 5-硝基-1-甲基-1H-苯并咪唑-2-丁酸乙酯
• 英文别名: (5-Nitro-1-Methyl-1H-benzo[d]iMidazol-2-yl)butanoic acid ethyl ester; TIANFU-CHEM - ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate; Bendamustine impurity (1-Methyl-5-nitro-1H-benzimidazole-2-butanoic Acid Ethyl Ester); Bendamustine ethyl ester impurity; Bendamustine Nitro Ethyl Ester; Ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl); 4-(1-Methyl-5-Nitro-1H-Benzo[D]Imidazol-2-Yl)Butanoate; Ethyl 4-(1-Methyl-5-nitro-1H-benzoimidazol-2-yl)-butyrate; ethyl 4-(1-methyl-5-nitro-1H-benzo[d]imidazol-2-yl)butanoate; 4-(1-methyl-5-nitro-2-benzimidazolyl)butanoic acid ethyl ester; Ibanic acid; ethyl 4-(1-Methyl-5-nitro-1H-1,3-benzodiazol-2-yl)butanoate; ETHYL 4-(1-METHYL-5-NITRO-1HBENZIMIDAZOL-2-YL) BUTANOATE; 2,2'-bipyridine, 5-(2,5-dimethyl-1h-pyrrol-1-yl); BendaMustine Nitro Ethyl Ester IMpurity; Bendamustine Impurity 30; 1H-BENZIMIDAZOLE-2-BUTANOIC ACID 1-METHY L-5-NITRO ETHYL ESTER DAM3P; Ethyl 4-(1-methyl-5-nitro-1H-benzimidazol-2-yl)butanoate; Bendamustine Related Impurity 18; 1H-Benzimidazole-2-butanoic acid, 1-methyl-5-nitro-, ethyl ester; 1-Methyl-5-nitro-1H-benzimidazole-2-butanoic acid ethyl ester; 1-Methyl-5-nitro-1H-benzimidazole-2-butanoic Acid Ethyl Ester-d3

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 481.0±25.0 °C at 760 mmHg
• 分子式: C₁₄H₁₇N₃O₄
• 分子量: 291.302
• 闪点: 244.7±23.2 °C
• 精确质量: 291.121918
• PSA: 89.94000
• LogP: 2.73
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.599
• 储存条件: 室温，干燥

安全

• 海关编码: 2933990090

合成路线

64-17-5 31349-48-1 ~93% 3543-72-4

文献：Heyl Chemisch-pharmazeutische Fabrik GmbH and Co. KG; Frey, Michael; Walther, Dirk-Detlef Patent: US2014/31560 A1, 2014 ; Location in patent: Paragraph 0101; 0102 ;

369-36-8 ~% 3543-72-4

文献：US2014/31560 A1, ;

108-55-4 ~% 3543-72-4

文献：US2014/31560 A1, ;

上下游产品

上游产品  4
64-17-5 31349-48-1 369-36-8 108-55-4
下游产品  4
3543-74-6 3543-75-7 3543-73-5 16506-27-7

海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%