444335-16-4

• 常用中文名：(5R)-3-(4-溴-3-氟苯基)-5-羟甲基恶唑烷-2-酮
• 常用英文名：(5r)-3-(4-bromo-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one
• CAS号：444335-16-4
• 分子式：C₁₀H₉BrFNO₃
• 分子量：290.086
• 发布时间：2018-08-01 14:04:05
• 更新时间：2024-01-09 10:00:17

名称

• 中文名: (5R)-3-(4-溴-3-氟苯基)-5-羟甲基恶唑烷-2-酮
• 英文名: (R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one
• 中文别名: (5R)-3-(4-溴-3-氟苯基)-5-羟基甲基噁唑啉-2-酮
• 英文别名: 2-Oxazolidinone, 3-(4-bromo-3-fluorophenyl)-5-(hydroxymethyl)-, (5R)-; (5R)-3-(4-Bromo-3-fluorophenyl)-5-(hydroxymethyl)-1,3-oxazolidin-2-one; (5r)-3-(4-bromo-3-fluorophenyl)-5-hydroxymethyloxazolidin-2-one

物化性质

• 密度: 1.7±0.1 g/cm3
• 沸点: 401.6±35.0 °C at 760 mmHg
• 分子式: C₁₀H₉BrFNO₃
• 分子量: 290.086
• 闪点: 196.7±25.9 °C
• 精确质量: 288.974976
• PSA: 49.77000
• LogP: 1.87
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.590
• 储存条件: 室温，干燥

安全

• 海关编码: 2934999090

合成路线

510729-01-8 60456-26-0 ~89% 444335-16-4

文献：LegoChem Biosciences, Inc.; CHO, Young Lag; BAEK, Sung Yoon; CHAE, Sang Eun; KIM, Sun Young; LEE, Hong Bum; LEE, Hyang Sook; OH, Kyuman; HEO, Hye Jin; PARK, Tae Kyo; WOO, Sung Ho; KIM, Yong Zu Patent: EP2692727 A2, 2014 ; Location in patent: Paragraph 0161-0162 ;

149524-42-5 ~% 444335-16-4

文献：GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT Patent: WO2009/120789 A1, 2009 ; Location in patent: Page/Page column 58 ;

60827-45-4 288570-67-2 ~% 444335-16-4

文献：Gordeev, Mikhail F.; Patel, Dinesh V.; Barbachyn, Michael R.; Gage, James R. Patent: US2003/13737 A1, 2003 ;

656-65-5 ~% 444335-16-4

文献：LegoChem Biosciences, Inc.; CHO, Young Lag; BAEK, Sung Yoon; CHAE, Sang Eun; KIM, Sun Young; LEE, Hong Bum; LEE, Hyang Sook; OH, Kyuman; HEO, Hye Jin; PARK, Tae Kyo; WOO, Sung Ho; KIM, Yong Zu Patent: EP2692727 A2, 2014 ;

上下游产品

上游产品  6
510729-01-8 60456-26-0 149524-42-5 60827-45-4
288570-67-2 656-65-5
下游产品  1
856677-05-9

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%