60598-48-3

• 常用中文名：5-氨基-1-苄基-1H-咪唑-4-甲腈
• 常用英文名：5-amino-1-benzyl-imidazole-4-carbonitrile
• CAS号：60598-48-3
• 分子式：C₁₁H₁₀N₄
• 分子量：198.22400
• 发布时间：2018-11-22 09:58:15
• 更新时间：2025-08-24 19:57:15

名称

• 中文名: 5-氨基-1-苄基-1H-咪唑-4-甲腈
• 英文名: 5-amino-1-benzylimidazole-4-carbonitrile
• 英文别名: 5-Amino-4-cyano-1-benzylimidazol; 5-Amino-1-benzyl-1H-imidazole-4-carbonitrile; 5-amino-4-cyano-1-benyzlimidazole; 5-Amino-1-benzyl-4-cyanoimidazole; 3-benzyl-4-amino-5-cyanoimidazole

物化性质

• 密度: 1.22g/cm3
• 沸点: 469.1ºC at 760 mmHg
• 分子式: C₁₁H₁₀N₄
• 分子量: 198.22400
• 闪点: 237.5ºC
• 精确质量: 198.09100
• PSA: 67.63000
• LogP: 1.96648
• 折射率: 1.649

合成路线

100-46-9 358657-89-3 ~72% 60598-48-3

文献：PFIZER LIMITED Patent: WO2006/117670 A1, 2006 ; Location in patent: Page/Page column 59 ;

133123-63-4 100-46-9 ~% 60598-48-3

文献：JANSSEN RandD IRELAND; BONFANTI, Jean-François; DOUBLET, Frédéric Marc Maurice; EMBRECHTS, Werner; FORTIN, Jérôme Michel Claude; MC GOWAN, David Craig; MULLER, Philippe; RABOISSON, Pierre Jean-Marie Bernard Patent: WO2013/68438 A1, 2013 ; Location in patent: Page/Page column 8 ;

100-39-0 5098-11-3 ~24% 4059-12-5 60598-48-3

文献：Grozinger; Freter; Farina; Gladczuk European Journal of Medicinal Chemistry, 1983 , vol. 18, # 3 p. 221 - 226

111267-84-6 ~% 60598-48-3

文献：Hosmane, Ramachandra S.; Lim, Benjamin B. Heterocycles, 1988 , vol. 27, # 1 p. 31 - 34

3815-69-8 ~71% 60598-48-3

文献：Costanzi, Stefano; Rouse, Sean P.N.; Vanbaelinghem, Laurence; Prior, Timothy J.; Ewing, David F.; Boa, Andrew N.; MacKenzie, Grahame Tetrahedron Letters, 2012 , vol. 53, # 4 p. 412 - 415

111267-83-5 100-46-9 ~86% 60598-48-3

文献：Hosmane, Ramachandra S.; Lim, Benjamin B.; Burnett, Friedrich N. Journal of Organic Chemistry, 1988 , vol. 53, # 2 p. 382 - 386

100-39-0 5098-11-3 ~23% 108575-59-3 4059-12-5 详细

文献：Grozinger; Onan Journal of Heterocyclic Chemistry, 1986 , vol. 23, # 3 p. 737 - 745

111267-86-8 ~47% 111267-87-9 60598-48-3

文献：Hosmane, Ramachandra S.; Lim, Benjamin B.; Burnett, Friedrich N. Journal of Organic Chemistry, 1988 , vol. 53, # 2 p. 382 - 386

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