25017-47-4

• 常用中文名：Urea,N-[2-(3,4-dimethoxyphenyl)ethyl]-
• 常用英文名：Urea,N-[2-(3,4-dimethoxyphenyl)ethyl]-
• CAS号：25017-47-4
• 分子式：C₁₁H₁₆N₂O₃
• 分子量：224.25600
• 发布时间：2016-07-31 17:22:59
• 更新时间：2024-03-31 17:43:52

名称

• 英文名: 2-(3,4-dimethoxyphenyl)ethylurea
• 英文别名: 1-(3,4-dimethoxyphenethyl)urea; N-(3,4-dimethoxyphenethyl)urea; (3,4-Dimethoxy-phenaethyl)-harnstoff; 1-2-(3,4-dimethoxyphenyl)ethyl urea; N-<2-(3,4-dimethoxyphenylethyl)>urea; Urea,(3,4-dimethoxyphenethyl); (3,4-dimethoxy-phenethyl)-urea

物化性质

• 密度: 1.141g/cm3
• 沸点: 367.6ºC at 760 mmHg
• 分子式: C₁₁H₁₆N₂O₃
• 分子量: 224.25600
• 闪点: 176.1ºC
• 精确质量: 224.11600
• PSA: 73.58000
• LogP: 2.00580
• 蒸汽压: 1.35E-05mmHg at 25°C
• 折射率: 1.533

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YS9863000 CHEMICAL NAME : Urea, (3,4-dimethoxyphenethyl)- CAS REGISTRY NUMBER : 25017-47-4 BEILSTEIN REFERENCE NO. : 2736376 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C11-H16-N2-O3 MOLECULAR WEIGHT : 224.29 WISWESSER LINE NOTATION : ZVM2R CO1 DO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >3 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 21,366,1969 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 336 mg/kg TOXIC EFFECTS : Behavioral - somnolence (general depressed activity) REFERENCE : JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 52,211,1934

合成路线

120-20-7 598-55-0 ~89% 25017-47-4

文献：Han, Chong; Porco Jr., John A. Organic Letters, 2007 , vol. 9, # 8 p. 1517 - 1520

590-28-3 120-20-7 ~% 25017-47-4

文献：Buck Journal of the American Chemical Society, 1934 , vol. 56, p. 1607

635-85-8 57-13-6 ~% 25017-47-4

文献：Ishii; Kotani; Nagaki; Shibayama; Toyomaki; Okukado; Ienaga; Okamoto Journal of Medicinal Chemistry, 1996 , vol. 39, # 9 p. 1924 - 1927

120-20-7 57-13-6 ~44% 25017-47-4

文献：Marugan, Juan J.; Zheng, Wei; Motabar, Omid; Southall, Noel; Goldin, Ehud; Sidransky, Ellen; Aungst, Ronald A.; Liu, Ke; Sadhukhan, Subir Kumar; Austin, Christopher P. European Journal of Medicinal Chemistry, 2010 , vol. 45, # 5 p. 1880 - 1897

35167-81-8 ~% 25017-47-4

文献：Fries; Bestian Justus Liebigs Annalen der Chemie, 1938 , vol. 533, p. 72,83

590-28-3 ~% 25017-47-4

文献：Jansen Recueil des Travaux Chimiques des Pays-Bas, 1931 , vol. 50, p. 617,621

51842-87-6 ~% 25017-47-4

文献：Fries; Bestian Justus Liebigs Annalen der Chemie, 1938 , vol. 533, p. 72,83

2107-70-2 ~% 25017-47-4

文献：Fries; Bestian Justus Liebigs Annalen der Chemie, 1938 , vol. 533, p. 72,83

21997-97-7 ~% 25017-47-4

文献：Fries; Bestian Justus Liebigs Annalen der Chemie, 1938 , vol. 533, p. 72,83

上下游产品

上游产品  8
120-20-7 598-55-0 590-28-3 635-85-8
57-13-6 35167-81-8 51842-87-6 2107-70-2
下游产品  3
76536-69-1 83070-40-0 80023-89-8