60789-87-9

• 常用中文名：1,2,3,4-Tetrahydrophthalazine hydrochloride
• 常用英文名：1,2,3,4-Tetrahydrophthalazine hydrochloride
• CAS号：60789-87-9
• 分子式：C₈H₁₁ClN₂
• 分子量：170.63900
• 发布时间：2016-12-26 11:21:13
• 更新时间：2025-08-25 12:20:24

名称

• 英文名: 1,2,3,4-tetrahydrophthalazine,hydrochloride
• 英文别名: 1,2,3,4-Tetrahydrophthalazine hydrochloride; hydrochloride salt of 1,2,3,4-tetrahydrophthalazine; 1,2,3,4-tetrahydrophthalazinehydrochloride(1:1); 1,2,3,4-Tetrahydrophthalazin-hydrochlorid; Ro 5-0994; Phtalazine,1,2,3,4-tetrahydro-,monohydrochloride; Phthalazine,1,2,3,4-tetrahydro-,hydrochloride

物化性质

• 密度: 1.045g/cm3
• 沸点: 233.4ºC at 760mmHg
• 分子式: C₈H₁₁ClN₂
• 分子量: 170.63900
• 闪点: 99.9ºC
• 精确质量: 170.06100
• PSA: 24.06000
• LogP: 2.25400

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TH9100000 CHEMICAL NAME : Phthalazine, 1,2,3,4-tetrahydro-, hydrochloride CAS REGISTRY NUMBER : 60789-87-9 LAST UPDATED : 199012 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C8-H10-N2.Cl-H MOLECULAR WEIGHT : 170.66 WISWESSER LINE NOTATION : T66 CMMT&J &GH HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 760 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,296,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 835 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,296,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 780 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,296,1972 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 380 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,296,1972

合成路线

253-52-1 ~61% 60789-87-9

文献：Morgenstern; Meusel; Denke; Vepsalainen; Richter Pharmazie, 1994 , vol. 49, # 6 p. 419 - 422

91-13-4 ~% 60789-87-9

文献：Groszkowski; Wesolowska Archiv der Pharmazie, 1981 , vol. 314, # 10 p. 880 - 884

80271-30-3 ~% 60789-87-9

文献：Groszkowski; Wesolowska Archiv der Pharmazie, 1981 , vol. 314, # 10 p. 880 - 884

80271-31-4 ~% 60789-87-9

文献：Groszkowski; Wesolowska Archiv der Pharmazie, 1981 , vol. 314, # 10 p. 880 - 884

80271-32-5 ~% 60789-87-9

文献：Groszkowski; Wesolowska Archiv der Pharmazie, 1981 , vol. 314, # 10 p. 880 - 884

上下游产品

上游产品  3
253-52-1 91-13-4 80271-31-4
下游产品  3
80271-33-6 80271-35-8 80271-36-9