5819-21-6

• 常用中文名：Carbamic acid,N-methyl-, 4-nitrophenyl ester
• 常用英文名：Carbamic acid,N-methyl-, 4-nitrophenyl ester
• CAS号：5819-21-6
• 分子式：C₈H₈N₂O₄
• 分子量：196.16000
• 发布时间：2017-11-26 20:41:26
• 更新时间：2025-08-27 14:43:50

名称

• 英文名: p-nitrophenyl N-methyl carbamate
• 英文别名: ETHYL-4-NITROPHENYLCARBAMATE; N-methyl-carbamate de p-nitrophenyle; p-NO2-C6H4OCONHCH3; 4-nitrophenyl N-methylcarbamate; N-methyl-(p-nitrophenyl carbamate)

物化性质

• 密度: 1.327g/cm3
• 沸点: 316.6ºC at 760mmHg
• 分子式: C₈H₈N₂O₄
• 分子量: 196.16000
• 闪点: 145.3ºC
• 精确质量: 196.04800
• PSA: 84.15000
• LogP: 2.22710
• 折射率: 1.559

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : FC6024000 CHEMICAL NAME : Carbamic acid, methyl-, 4-nitrophenyl ester CAS REGISTRY NUMBER : 5819-21-6 LAST UPDATED : 199703 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C8-H8-N2-O4 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >80 mg/kg TOXIC EFFECTS : Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation REFERENCE : NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: PB158-508

合成路线

100-02-7 624-83-9 ~85% 5819-21-6

文献：Martinez; Oiry; Imbach; Winternitz European Journal of Medicinal Chemistry, 1980 , vol. 15, # 3 p. 211 - 213

593-51-1 7693-46-1 ~90% 5819-21-6

文献：Peterson, Matt A.; Shi, Houguang; Ke, Pucheng Tetrahedron Letters, 2006 , vol. 47, # 20 p. 3405 - 3407

100-02-7 30379-59-0 ~86% 5819-21-6

文献：Deshpande, Sunita R.; Likhite, Anjali P.; Rajappa, Srinivasachari Tetrahedron, 1994 , vol. 50, # 34 p. 10367 - 10370

100-02-7 6642-30-4 ~31% 5819-21-6

文献：Kumaran, G.; Naik, R. H.; Kulkarni, G. H. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1993 , vol. 32, # 8 p. 893 - 895

100-02-7 ~% 5819-21-6

文献：Konakahara; Ozaki; Sato; Gold Synthesis, 1993 , # 1 p. 103 - 106

上下游产品

上游产品  6
100-02-7 624-83-9 593-51-1 7693-46-1
30379-59-0 6642-30-4
下游产品  1
6135-36-0