208108-75-2

• 常用中文名：4-苯基-5-(三氟甲基)噻吩-2-羰基氯
• 常用英文名：4-PHENYL-5-(TRIFLUOROMETHYL)-2-THIOPHENECARBONYL CHLORIDE
• CAS号：208108-75-2
• 分子式：C₁₂H₆ClF₃OS
• 分子量：290.68900
• 发布时间：2018-08-01 18:01:47
• 更新时间：2025-09-03 22:08:40

名称

• 中文名: 4-苯基-5-(三氟甲基)-2-噻吩羧酸酰氯
• 英文名: 4-phenyl-5-(trifluoromethyl)thiophene-2-carbonyl chloride
• 英文别名: 5-trifluoromethyl-4-phenyl-thiophene-2-carboxylic acid chloride

物化性质

• 密度: 1.424g/cm3
• 沸点: 161/0.5mm
• 熔点: 48ºC
• 分子式: C₁₂H₆ClF₃OS
• 分子量: 290.68900
• 闪点: 156.6ºC
• 精确质量: 289.97800
• PSA: 45.31000
• LogP: 4.81290
• 蒸汽压: 0.000121mmHg at 25°C
• 折射率: 1.544

合成路线

208108-76-3 ~% 208108-75-2

文献：BRISTOL-MYERS SQUIBB COMPANY; GILMORE, John L.; SHEPPECK, James E. Patent: WO2011/17578 A1, 2011 ; Location in patent: Page/Page column 178-179 ;

79-37-8 208108-76-3 ~% 208108-75-2

文献：Bayer Aktiengesellschaft Patent: US6013664 A1, 2000 ;

350-92-5 ~% 208108-75-2

文献：Hale, Jeffrey J.; Lynch, Christopher L.; Neway, William; Mills, Sander G.; Hajdu, Richard; Keohane, Carol Ann; Rosenbach, Mark J.; Milligan, James A.; Shei, Gan-Ju; Parent, Stephen A.; Chrebet, Gary; Bergstrom, James; Card, Deborah; Ferrer, Marc; Hodder, Peter; Strulovici, Berta; Rosen, Hugh; Mandala, Suzanne Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6662 - 6665

119197-24-9 ~% 208108-75-2

文献：Hale, Jeffrey J.; Lynch, Christopher L.; Neway, William; Mills, Sander G.; Hajdu, Richard; Keohane, Carol Ann; Rosenbach, Mark J.; Milligan, James A.; Shei, Gan-Ju; Parent, Stephen A.; Chrebet, Gary; Bergstrom, James; Card, Deborah; Ferrer, Marc; Hodder, Peter; Strulovici, Berta; Rosen, Hugh; Mandala, Suzanne Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6662 - 6665

167279-18-7 ~% 208108-75-2

文献：Hale, Jeffrey J.; Lynch, Christopher L.; Neway, William; Mills, Sander G.; Hajdu, Richard; Keohane, Carol Ann; Rosenbach, Mark J.; Milligan, James A.; Shei, Gan-Ju; Parent, Stephen A.; Chrebet, Gary; Bergstrom, James; Card, Deborah; Ferrer, Marc; Hodder, Peter; Strulovici, Berta; Rosen, Hugh; Mandala, Suzanne Journal of Medicinal Chemistry, 2004 , vol. 47, # 27 p. 6662 - 6665

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