113533-65-6

• 常用中文名：1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 常用英文名：1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid
• CAS号：113533-65-6
• 分子式：C₁₈H₂₁FN₄O₃
• 分子量：360.38300
• 发布时间：2017-05-28 01:05:43
• 更新时间：2024-04-05 18:48:57

名称

• 英文名: 1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 英文别名: 1-cyclopropyl-6-fluoro-1,4-dihydro-7-<3-<(methylamino)methyl>-1-pyrrolidinyl>-4-oxo-1,8-naphthyridine-3-carboxylic acid; 3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo[3.2.1]oct-3-yl)-4-oxo; 8,-naphthyridine-3-carboxylic acid; 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[3-[(methylamino)methyl]-1-pyrrolidinyl]-4-oxo-1; 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo[3.2.1]oct-3-yl)-4-oxo-3-quinoline carboxylic acid; CP-74,667

物化性质

• 密度: 1.426g/cm3
• 沸点: 581.8ºC at 760 mmHg
• 分子式: C₁₈H₂₁FN₄O₃
• 分子量: 360.38300
• 闪点: 305.7ºC
• 精确质量: 360.16000
• PSA: 87.46000
• LogP: 2.07030
• 蒸汽压: 2.23E-14mmHg at 25°C
• 折射率: 1.639

合成路线

91187-81-4 100361-18-0 ~85% 113533-65-6

文献：Sanchez, Joseph P.; Domagala, John M.; Hagen, Susan E.; Heifetz, Carl L.; Hutt, Marland P.; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, p. 983 - 991

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