342816-00-6

• 常用中文名：BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE
• 常用英文名：BETA,BETA-DIFLUORO-2-PYRIDINEETHANAMIN,1-OXIDE
• CAS号：342816-00-6
• 分子式：C₇H₈F₂N₂O
• 分子量：174.14800
• 发布时间：2017-02-04 04:57:07
• 更新时间：2024-02-17 19:35:45

名称

• 英文名: 2,2-difluoro-2-(1-oxidopyridin-1-ium-2-yl)ethanamine
• 英文别名: 2,2-difluoro-2-(2-pyridyl)ethyl-trifluoromethanesulfonate; 2,2-difluoro-2-(1-oxido-2-pyridyl)ethanamine; 2,2-difluoro-2-pyridin-2-yl-ethylamine N-oxide; 2,2-difluoro-2-pyridin-2-ylethyl trifluoromethanesulfonate; 2,2-difluoro-2-(2-pyridyl-N-oxide)ethylamine; 2,2-difluoro-2-(1-oxy-pyridin-2-yl)-ethylamine; Methanesulfonic acid,trifluoro-,2,2-difluoro-2-(2-pyridinyl)ethyl ester; 2,2-difluoro-2-(1-oxido-2-pyridintl)ethylamine; 2,2-difluoro-2-(1-oxido-pyridin-2-yl)ethanamine

物化性质

• 分子式: C₇H₈F₂N₂O
• 分子量: 174.14800
• 精确质量: 174.06000
• PSA: 51.48000
• LogP: 1.86590

合成路线

342815-99-0 ~97% 342816-00-6

文献：Chen, Li; Chen, Shaoqing Patent: US2006/4045 A1, 2006 ; Location in patent: Page/Page column 25 ; US 20060004045 A1

267875-67-2 ~% 342816-00-6

文献：Burgey, Christopher S.; Robinson, Kyle A.; Lyle, Terry A.; Nantermet, Philippe G.; Selnick, Harold G.; Isaacs, Richard C.A.; Lewis, S. Dale; Lucas, Bobby J.; Krueger, Julie A.; Singh, Rominder; Miller-Stein, Cynthia; White, Rebecca B.; Wong, Bradley; Lyle, Elizabeth A.; Stranieri, Maria T.; Cook, Jacquelynn J.; McMasters, Daniel R.; Pellicore, Janetta M.; Pal, Swati; Wallace, Audrey A.; Clayton, Franklin C.; Bohn, Dennis; Welsh, Denise C.; Lynch Jr., Joseph J.; Yan, Youwei; Chen, Zhongguo; Kuo, Lawrence; Gardell, Stephen J.; Shafer, Jules A.; Vacca, Joseph P. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 7 p. 1353 - 1357