761440-65-7

• 常用中文名：1-(1-(3-甲氧基-4-硝基苯基)哌啶-4-基)-4-甲基哌嗪
• 常用英文名：1-(1-(3-Methoxy-4-nitrophenyl)piperidin-4-yl)-4-Methylpiperazine
• CAS号：761440-65-7
• 分子式：C₁₇H₂₆N₄O₃
• 分子量：334.413
• 发布时间：2018-12-30 21:42:19
• 更新时间：2024-01-13 22:20:15

名称

• 中文名: 1-(1-(3-甲氧基-4-硝基苯基)哌啶-4-基)-4-甲基哌嗪
• 英文名: 1-[1-(3-Methoxy-4-nitrophenyl)-4-piperidinyl]-4-methylpiperazine
• 英文别名: 1-[1-(3-Methoxy-4-nitrophenyl)-4-piperidinyl]-4-methylpiperazine; 1-[1-(3-cyano-3,3-diphenyl-propyl)-piperidin-4-yl]-3-propionyl-1,3-dihydro-benzoimidazol-2-one; Bezitramida [INN-Spanish]; BEZITRAMIDE; Piperazine, 1-[1-(3-methoxy-4-nitrophenyl)-4-piperidinyl]-4-methyl-; Bezitramidum [INN-Latin]; Burgodin; 1-[1-(3-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine; benzitramide

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 488.9±45.0 °C at 760 mmHg
• 分子式: C₁₇H₂₆N₄O₃
• 分子量: 334.413
• 闪点: 249.5±28.7 °C
• 精确质量: 334.200500
• PSA: 64.77000
• LogP: 1.64
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.576
• 储存条件: 2-8℃

合成路线

448-19-1 53617-36-0 ~90% 761440-65-7

文献：ABBOTT LABORATORIES Patent: US2011/15172 A1, 2011 ; Location in patent: Page/Page column 34 ;

109-01-3 761440-64-6 ~89% 761440-65-7

文献：NOVARTIS AG; NOVARTIS PHARMA GMBH Patent: WO2004/80980 A1, 2004 ; Location in patent: Page 132 ; WO 2004/080980 A1

448-19-1 ~% 761440-65-7

文献：Astellas Pharma Inc.; OBITSU, Kazuyoshi; AKIBA, Takahiro; KOBAYASHI, Koji; HIRASAWA, Shun; KONDOH, Yutaka; TAKEGUCHI, Kazuhiro; TAKAHAMA, Yuji; ORII, Ryoki Patent: EP2669281 A1, 2013 ;

41979-39-9 ~% 761440-65-7

文献：Astellas Pharma Inc.; OBITSU, Kazuyoshi; AKIBA, Takahiro; KOBAYASHI, Koji; HIRASAWA, Shun; KONDOH, Yutaka; TAKEGUCHI, Kazuhiro; TAKAHAMA, Yuji; ORII, Ryoki Patent: EP2669281 A1, 2013 ;

上下游产品

上游产品  5
448-19-1 53617-36-0 109-01-3 761440-64-6
41979-39-9
下游产品  1
1097917-15-1