616202-81-4

• 常用中文名：(S)-8-氯-1-甲基-2,3,4,5-四氢-1H-3-苯并氮杂卓
• 常用英文名：1H-3-Benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-Methyl-, (1S)-
• CAS号：616202-81-4
• 分子式：C₁₁H₁₄ClN
• 分子量：195.689
• 发布时间：2018-06-11 18:28:41
• 更新时间：2025-11-30 06:52:09

名称

• 中文名: 绿卡色林中间体-7
• 英文名: (5S)-7-chloro-5-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine
• 英文别名: 1H-3-Benzazepine, 8-chloro-2,3,4,5-tetrahydro-1-methyl-; 1H-3-Benzazepine,8-chloro-2,3,4,5-tetrahydro-1-methyl-,(1S); 8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine; 8-Chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 288.1±40.0 °C at 760 mmHg
• 分子式: C₁₁H₁₄ClN
• 分子量: 195.689
• 闪点: 128.1±27.3 °C
• 精确质量: 195.081482
• PSA: 12.03000
• LogP: 2.89
• 蒸汽压: 0.0±0.6 mmHg at 25°C
• 折射率: 1.527

合成路线

616202-78-9 ~97% 616202-81-4

文献：ARENA PHARMACEUTICALS, INC. Patent: WO2005/42491 A1, 2005 ; Location in patent: Page/Page column 43 ; WO 2005/042491 A1

34164-14-2 ~% 616202-81-4

文献：Smith, Brian M.; Smith, Jeffrey M.; Tsai, James H.; Schultz, Jeffrey A.; Gilson, Charles A.; Estrada, Scott A.; Chen, Rita R.; Park, Douglas M.; Prieto, Emily B.; Gallardo, Charlemagne S.; Sengupta, Dipanjan; Thomsen, William J.; Saldana, Hazel R.; Whelan, Kevin T.; Menzaghi, Frederique; Webb, Robert R.; Beeley, Nigel R.A. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 5 p. 1467 - 1470

156-41-2 ~% 616202-81-4

文献：Smith, Brian M.; Smith, Jeffrey M.; Tsai, James H.; Schultz, Jeffrey A.; Gilson, Charles A.; Estrada, Scott A.; Chen, Rita R.; Park, Douglas M.; Prieto, Emily B.; Gallardo, Charlemagne S.; Sengupta, Dipanjan; Thomsen, William J.; Saldana, Hazel R.; Whelan, Kevin T.; Menzaghi, Frederique; Webb, Robert R.; Beeley, Nigel R.A. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 5 p. 1467 - 1470

824430-77-5 ~% 616202-81-4

文献：Smith, Brian M.; Smith, Jeffrey M.; Tsai, James H.; Schultz, Jeffrey A.; Gilson, Charles A.; Estrada, Scott A.; Chen, Rita R.; Park, Douglas M.; Prieto, Emily B.; Gallardo, Charlemagne S.; Sengupta, Dipanjan; Thomsen, William J.; Saldana, Hazel R.; Whelan, Kevin T.; Menzaghi, Frederique; Webb, Robert R.; Beeley, Nigel R.A. Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 5 p. 1467 - 1470

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